The pathogenesis of tuberculous meningitis

AG Davis, UK Rohlwink, A Proust… - Journal of leukocyte …, 2019 - academic.oup.com
Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

[HTML][HTML] Role of calcium modulation in the pathophysiology and treatment of Alzheimer's disease

D Baracaldo-Santamaría, SS Avendaño-Lopez… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most frequent
cause of progressive dementia in senior adults. It is characterized by memory loss and …

[HTML][HTML] Marine sources of DHA-rich phospholipids with anti-Alzheimer effect

I Ferreira, AP Rauter, NM Bandarra - Marine Drugs, 2022 - mdpi.com
Alzheimer's disease (AD) is a complex and progressive disease, which affects millions of
people around the world. Despite the many efforts over the years to find efficient …

[HTML][HTML] Common signaling pathways involved in Alzheimer's disease and stroke: Two Faces of the Same Coin

TK Das, BP Ganesh… - Journal of Alzheimer's …, 2023 - content.iospress.com
Alzheimer's disease (AD) and stroke are two interrelated neurodegenerative disorders
which are the leading cause of death and affect the neurons in the brain and central nervous …

[HTML][HTML] The effect of age and sex on the expression of GABA signaling components in the human hippocampus and entorhinal cortex

J Ethiraj, TH Palpagama, C Turner, B van der Werf… - Scientific reports, 2021 - nature.com
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the nervous
system. The GABA signaling system in the brain is comprised of GABA synthesizing …

[HTML][HTML] Females exhibit higher GluA2 levels and outperform males in active place avoidance despite increased amyloid plaques in TgF344-Alzheimer's rats

O Chaudry, K Ndukwe, L Xie, M Figueiredo-Pereira… - Scientific Reports, 2022 - nature.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is most prevalent
in females. While estrogen provides neuroprotection in females, sex mediated differences in …

[HTML][HTML] NMDA receptor C-terminal domain signalling in development, maturity, and disease

K Haddow, PC Kind, GE Hardingham - International Journal of Molecular …, 2022 - mdpi.com
The NMDA receptor is a Ca2+-permeant glutamate receptor which plays key roles in health
and disease. Canonical NMDARs contain two GluN2 subunits, of which 2A and 2B are …

[HTML][HTML] Glutamate Receptor Dysregulation and Platelet Glutamate Dynamics in Alzheimer's and Parkinson's Diseases: Insights into Current Medications

D Gautam, UP Naik, MU Naik, SK Yadav… - Biomolecules, 2023 - mdpi.com
Two of the most prevalent neurodegenerative disorders (NDDs), Alzheimer's disease (AD)
and Parkinson's disease (PD), present significant challenges to healthcare systems …

[HTML][HTML] EAAT2 expression in the hippocampus, subiculum, entorhinal cortex and superior temporal gyrus in Alzheimer's disease

JHY Yeung, TH Palpagama, OWG Wood… - Frontiers in Cellular …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neuropathological disorder characterized by the presence and
accumulation of amyloid-beta plaques and neurofibrillary tangles. Glutamate dysregulation …

[HTML][HTML] Roles of traditional chinese medicine regulating neuroendocrinology on AD treatment

C Deng, H Chen, Z Meng, S Meng - Frontiers in Endocrinology, 2022 - frontiersin.org
The incidence of sporadic Alzheimer's disease (AD) is increasing in recent years. Studies
have shown that in addition to some genetic abnormalities, the majority of AD patients has a …