Aging is the progressive loss of organ and tissue function over time. Growing older is
positively linked to cognitive and biological degeneration such as physical frailty …

Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming
incidence rate and a huge burden on health care providers. DM is characterized by the …

Diabetic neuropathy is regarded as one of the most debilitating outcomes of diabetes
mellitus and may cause pain, decreased motility, and even amputation. Diabetic neuropathy …

Doxorubicin (DOX) is an anthracycline antibiotic that is used extensively for the
management of carcinoma; however, its clinical application is limited due to its serious …

Type 2 diabetes mellitus (DM) has reached pandemic proportions and effective prevention
strategies are wanted. Its onset is accompanied by cellular distress, the nuclear factor …

Neurodegenerative disorders pose a significant health burden and imprint a debilitative
impact on the quality of life. Importantly, aging is intricately intertwined with the progression …

Aims Hyperglycemia-mediated oxidative damage has been described as a major
mechanism leading to pathologic changes associated with diabetic cardiomyopathy (DCM) …

Western lifestyle contributes to an overt increase in the prevalence of metabolic anomalies
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …

The global prevalence of diabetes continues to increase partly due to rapid urbanization and
an increase in the aging population. Consequently, this is associated with a parallel …