Transfusion-transmitted infections (TTI) have been greatly reduced in numbers due to the
strict donor selection and screening procedures, ie the availability of technologies to test …

Microparticles are small membrane-bound vesicles found in body fluids including peripheral
blood. Microparticles are an intrinsic part of blood labile products delivered to transfused …

The ability to create a platelet product for transfusion purposes has existed for more than 50
years, 1 and has contributed to fundamental changes in the practice of transfusion medicine …

Platelets are currently acknowledged as cells of innate immunity and inflammation and play
a complex role in sepsis. We examined whether different types of LPS have different effects …

Platelet function in thrombosis and haemostasis is reasonably well understood at the
molecular level with respect to the proteins involved in cellular structure, signalling networks …

Plasma membrane-derived microvesicles or microparticles (MPs) are sub-cellular vesicles
released upon shear stress, cell activation, injury or apoptosis. They represent factors of the …

Background Platelet concentrates (PC s) can be prepared using three methods: platelet
(PLT)‐rich plasma, apheresis, and buffy coat. The aim of this study was to obtain a …

Background Platelets participate in tissue repair and innate immune responses. Sialic acid-
binding immunoglobulin-like lectins (Siglecs) are well-characterized I-type lectins, which …

Blood platelets play a pivotal role in thrombosis and haemostasis. Platelet transfusions are
life-saving medical procedures for patients undergoing major surgery or suffering from …

For patients with platelet deficiencies, platelet components are therapeutic products for
which there is no substitute. However, transfusion complications are more frequent with this …