Exploring protein-protein interactions at the proteome level
Proteins are central to all of the processes of life. For their activity, they almost invariably
need to interact with other macromolecules, be they nucleic acids, membranes, glycans, or …
need to interact with other macromolecules, be they nucleic acids, membranes, glycans, or …
Optimizing Cryo-FIB lamellas for sub-5Å in situ structural biology
S Khavnekar, V Vrbovská, M Zaoralová, R Kelley… - BioRXiv, 2022 - biorxiv.org
We here present a method based on metallic platinum sputtering that can substantially
enhance the quality of subtomogram averages from lamellas and thereby reduce the …
enhance the quality of subtomogram averages from lamellas and thereby reduce the …
An optimized approach to study nanoscale sarcomere structure utilizing super-resolution microscopy with nanobodies
The sarcomere is the fundamental contractile unit in skeletal muscle, and the regularity of its
structure is critical for function. Emerging data demonstrates that nanoscale changes to the …
structure is critical for function. Emerging data demonstrates that nanoscale changes to the …
An optimized approach to study sub-sarcomere structure utilizing super-resolution microscopy with secondary VHH nanobodies
The sarcomere is the fundamental contractile unit in skeletal muscle, and the maintenance
of its structure is critical for its function. While alterations in sarcomere structure are …
of its structure is critical for its function. While alterations in sarcomere structure are …