Oxidative stress and antioxidants in uterine fibroids: pathophysiology and clinical implications

A AlAshqar, B Lulseged, A Mason-Otey, J Liang… - Antioxidants, 2023 - mdpi.com
In the last few decades, our understanding of the complex pathobiology of uterine fibroid
development has grown. While previously believed to be a purely neoplastic entity, we now …

The relationship between spiritual health and COVID-19 anxiety among nurses: a national online cross-sectional study

A Davarinia Motlagh Quchan, F Mohammadzadeh… - Scientific Reports, 2024 - nature.com
Abstract The Coronavirus disease 2019 (COVID-19) outbreak has created many concerns in
most countries. Nurses are among healthcare workers who are largely engaged in providing …

The influence of race/ethnicity on the transcriptomic landscape of uterine fibroids

TD Chuang, N Ton, S Rysling, D Quintanilla… - International journal of …, 2023 - mdpi.com
The objective of this study was to determine if the aberrant expression of select genes could
form the basis for the racial disparity in fibroid characteristics. The next-generation RNA …

Identification and validation of prognosis-associated DNA repair gene signatures in colorectal cancer

D Song, D Zhang, S Chen, J Wu, Q Hao, L Zhao… - Scientific Reports, 2022 - nature.com
Colorectal cancer (CRC) is the third most common malignant tumor. DNA damage plays a
crucial role in tumorigenesis, and abnormal DNA repair pathways affect the occurrence and …

Age of first diagnosis and incidence rate of uterine fibroids in Ghana. A retrospective cohort study

EKM Edzie, K Dzefi-Tettey, EK Brakohiapa, F Quarshie… - Plos one, 2023 - journals.plos.org
Background Uterine fibroids are benign tumors that grow in or on the uterus of women.
Globally, they occur in more than 80% of women of African ancestry and 70% in white …

High-throughput screening platform for nanoparticle-mediated alterations of DNA repair capacity

SM Toprani, D Bitounis, Q Huang, N Oliveira, KW Ng… - ACS …, 2021 - ACS Publications
The potential genotoxic effects of engineered nanomaterials (ENMs) may occur through the
induction of DNA damage or the disruption of DNA repair processes. Inefficient DNA repair …

Further characterization of tryptophan metabolism and its dysregulation in fibroids

TD Chuang, D Quintanilla, D Boos, O Khorram - F&S Science, 2022 - Elsevier
Objective To determine the expression of enzymes in tryptophan (Trp) catabolism in fibroids
and matched myometrium and determine the effects of race and mediator complex subunit …

The effect of race/ethnicity and MED12 mutation on the expression of long non-coding RNAs in uterine leiomyoma and myometrium

TD Chuang, N Ton, S Rysling, D Boos… - International journal of …, 2024 - mdpi.com
The objective of this study was to elucidate the expression of long non-coding RNA
(lncRNA) in leiomyomas (Lyo) and paired myometrium (Myo) and explore the impact of race …

Magnetic resonance-guided high-intensity ultrasound (MR-HIFU) in the treatment of symptomatic uterine fibroids—Five-year experience

T Lozinski, J Filipowska, M Pyka… - Ginekologia …, 2022 - journals.viamedica.pl
Objectives: Uterine fibroids (UF) are the most common benign tumors of the female
reproductive organ. It is crucial to recognize that the appropriate treatment of UFs requires …

Endocrine-disrupting chemicals and Vitamin D deficiency in the pathogenesis of uterine fibroids

H Elkafas, OA Badary, E Elmorsy, R Kamel… - Journal of advanced …, 2021 - journals.ekb.eg
Uterine fibroids (UFs) are the most prevalent gynecologic neoplasm, affecting 70–80% of
women over their lifespan. Although UFs are benign, they can become life-threatening and …