[HTML][HTML] The IRE1α/XBP1 pathway sustains cytokine responses of group 3 innate lymphoid cells in inflammatory bowel disease

S Cao, JL Fachi, K Ma, AU Antonova, Q Wang… - The Journal of Clinical …, 2024 - jci.org
Group 3 innate lymphoid cells (ILC3s) are key players in intestinal homeostasis. ER stress is
linked to inflammatory bowel disease (IBD). Here, we used cell culture, mouse models, and …

Crosstalk between hypoxia-inducible factor-1α and short-chain fatty acids in inflammatory bowel disease: key clues toward unraveling the mystery

J Xiao, X Guo, Z Wang - Frontiers in Immunology, 2024 - frontiersin.org
The human intestinal tract constitutes a complex ecosystem, made up of countless gut
microbiota, metabolites, and immune cells, with hypoxia being a fundamental environmental …

The microbiome's influence on obesity: mechanisms and therapeutic potential

DA Tadese, J Mwangi, L Luo, H Zhang… - Science China Life …, 2024 - Springer
Abstract In 2023, the World Obesity Atlas Federation concluded that more than 50% of the
world's population would be overweight or obese within the next 12 years. At the heart of this …

Hyperbaric oxygen therapy alleviates intestinal dysfunction following traumatic brain injury via m6A regulation

X Yu, W Zhao, Y Liu, J Lv, X Zhong… - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Hyperbaric oxygen (HBO) therapy can attenuate neurological impairment after traumatic
brain injury (TBI) and alleviate intestinal dysfunction. However, the role and mechanism of …

Nesfatin-1 Is Involved in Hyperbaric Oxygen-Mediated Therapeutic Effects in High Fat Diet-Induced hyperphagia in Mice

Y Xie, Y Feng, S Li, B Yu, F Yang, Y Li, Y Cheng, Z Yu… - Peptides, 2024 - Elsevier
Obesity is a worldwide health issue. Effective and safe methods for obesity management are
highly desirable. In the current study, hyperbaric oxygen (HBO) treatment was investigated …