Offset analgesia (OA) is observed when pain relief is disproportional to the reduction of
noxious input and is based on temporal contrast enhancement (TCE). This phenomenon is …

Background Offset analgesia (OA) is characterized by a disproportionately large reduction in
pain following a small decrease in noxious stimulation and is based on temporal pain …

A frequently used paradigm to quantify endogenous pain modulation is offset analgesia,
which is defined as a disproportionate large reduction in pain following a small decrease in …

Objectives: To investigate the relationship between offset analgesia magnitude and the
responsiveness to conditioned pain modulation (CPM), temporal summation of (second) …

Background Offset analgesia (OA) is commonly used to quantify endogenous pain inhibition.
However, the potential role of afferent inputs and the subsequent peripheral factors from …

Knee pain is associated with lower muscle strength, and both contribute to disability.
Peripheral and central neurological mechanisms contribute to OA pain. Understanding the …

Offset analgesia (OA) is believed to reflect the efficiency of the endogenous pain modulatory
system. However, the underlying mechanisms are still being debated. Previous research …

Objectives Offset analgesia (OA) is the phenomenon where the perceived pain intensity to
heat stimulation disproportionally decreases after a slight decrease in stimulation …

Objectives: In this study, 2 separate experiments were conducted to investigate both, the
spatial aspects of offset analgesia and the influence of different rates of temperature rise …

Background: Offset analgesia (OA) is characterized by a disproportionately large reduction
in pain following a small decrease in noxious stimulation and is based on temporal pain …