NMDA receptors (NMDARs) play an important role in neural plasticity including long-term
potentiation and long-term depression, which are likely to explain their importance for …

Glutamatergic transmission in schizophrenia: from basic rese... : Current Opinion in Psychiatry
Glutamatergic transmission in schizophrenia: from basic research to clinical practice : Current …

The elevation of kynurenic acid (KYNA) observed in schizophrenic patients may contribute
to core symptoms arising from glutamate hypofunction, including cognitive impairments …

Background N-methyl-D-aspartate receptor (NMDAR)-mediated neurotransmission is vital
for learning and memory. Hypofunction of NMDAR has been reported to play a role in the …

The NMDA receptor (NMDAR) family of l-glutamate receptors are well known to have
diverse roles in CNS function as well as in various neuropathological and psychiatric …

Over the years, accumulating evidence has indicated that D-serine represents the
endogenous ligand for the glycinemodulatory binding site on the NR1 subunit of N-methyl-D …

Isatin (indole-2, 3-dione) is an endogenous regulator, exhibiting various behavioral,
biological, and pharmacological activities. Synthesis of isatin includes several crucial …

Dementia has become an all-important disease because the population is aging rapidly and
the cost of health care associated with dementia is ever increasing. In addition to cognitive …

Abstract N-methyl-d-aspartate (NMDA) receptor hypofunctionality is a well-studied
hypothesis for schizophrenia pathophysiology, and daily dosing of the NMDA receptor co …

d-Amino-acid oxidase (DAO) catalyzes the oxidative deamination of d-amino acids. DAO is
present in a wide variety of organisms and has important roles. Here, we review the …