[HTML][HTML] Pyridine: the scaffolds with significant clinical diversity

S De, AK SK, SK Shah, S Kazi, N Sarkar, S Banerjee… - Rsc Advances, 2022 - pubs.rsc.org
The nitrogen-bearing heterocycle pyridine in its several analogous forms occupies an
important position as a precious source of clinically useful agents in the field of medicinal …

[PDF][PDF] A review on the medicinal importance of pyridine derivatives

AA Altaf, A Shahzad, Z Gul, N Rasool… - J. Drug Des. Med …, 2015 - researchgate.net
Pyridine and its derivatives are the important chemical compounds with tremendous
applications in the various fields. In this review we have summarized the medicinal and non …

Quinoline and quinolone dimers and their biological activities: An overview

XM Chu, C Wang, W Liu, LL Liang, KK Gong… - European journal of …, 2019 - Elsevier
Quinoline and quinolone motifs which act as structural subunits of more complex natural
products are ubiquitous in nature, and they are useful pharmacophores which play a pivotal …

[HTML][HTML] Quinoline: A versatile heterocyclic

A Marella, OP Tanwar, R Saha, MR Ali… - Saudi Pharmaceutical …, 2013 - Elsevier
Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to
possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti …

Antiviral activities of pyridine fused and pyridine containing heterocycles, a review (from 2000 to 2020)

SR Alizadeh, MA Ebrahimzadeh - Mini Reviews in Medicinal …, 2021 - ingentaconnect.com
Heterocyclic compounds play a critical role in medicinal chemistry, and many available
drugs contain heterocyclic rings. A six-membered heterocyclic compound, pyridine, showed …

Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance

V Pokrovskaya, T Baasov - Expert opinion on drug discovery, 2010 - Taylor & Francis
Importance of the field: The emerging and sustained resistance to currently available
antibiotics and the poor pipeline of new antibacterials urgently call for the development of …

Novel pyrazolo [3, 4-b] pyridine derivatives: Synthesis, characterization, antimicrobial and antiproliferative profile

MS Salem, MAM Ali - Biological and Pharmaceutical Bulletin, 2016 - jstage.jst.go.jp
Three novel series of pyridine derivatives, namely Schiff's bases, 4-thiazolidinones and
azetidin-2-ones bearing pyrazolo [3, 4-b] pyridine moiety, have been synthesized. The …

Visible-light-mediated synthesis of quinolines

AK Dhiya, A Monga, A Sharma - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Quinolines are N-heterocyclic privileged scaffolds that find immense applications in
biological domains and materials science. For example, they act as antimalarial, anti …

Synthesis of pyridine derivatives for diverse biological activity profiles: a review

TR Allaka, NK Katari - Recent Developments in the Synthesis and …, 2023 - Elsevier
Pyridine (py) is one of the important heterocyclic compounds and an internal part of several
natural products. There are various medicines containing pyridine ring system being …

Synthesis, molecular modeling Insights, and anticancer assessment of novel polyfunctionalized Pyridine congeners

MG Abouelenein, AA El-Rashedy, HM Awad… - Bioorganic …, 2023 - Elsevier
The present study describes synthesizing a novel series of polyfunctionalized pyridine
congeners 1–18 and assessed for cytotoxic efficacies versus HCT-116, MCF-7, and HepG-2 …