Charting Alzheimer's disease and dementia: epidemiological insights, risk factors and prevention pathways

I Contador, B Buch-Vicente, T Del Ser… - Journal of Clinical …, 2024 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD), the most common cause of dementia, is a complex and
multifactorial condition without cure at present. The latest treatments, based on anti-amyloid …

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging …

T Ninomiya, S Nakaji, T Maeda, M Yamada… - … Health and Preventive …, 2020 - Springer
Background The burden of dementia is growing rapidly and has become a medical and
social problem in Japan. Prospective cohort studies have been considered an effective …

[HTML][HTML] Salud mental en el adulto mayor: trastornos neurocognitivos mayores, afectivos y del sueño

T Tello-Rodríguez, RD Alarcón… - Revista Peruana de …, 2016 - SciELO Public Health
Existen numerosos factores biológicos, psicológicos y sociales con impacto más o menos
prominente en la salud mental de las personas adultas mayores. Aparte de componentes …

Observational studies in Alzheimer disease: bridging preclinical studies and clinical trials

WD Brenowitz, K Yaffe - Nature Reviews Neurology, 2022 - nature.com
Recent high-profile failures of Alzheimer disease treatments at the clinical trial stage have
led to renewed efforts to identify and test novel interventions for Alzheimer disease and …

Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts

G Weinstein, KL Davis-Plourde, S Conner, JJ Himali… - PloS one, 2019 - journals.plos.org
Objective To determine whether classes of diabetes medications are associated with
cognitive health and dementia risk, above and beyond their glycemic control properties …

Big data and dementia: charting the route ahead for research, ethics, and policy

M Ienca, E Vayena, A Blasimme - Frontiers in medicine, 2018 - frontiersin.org
Emerging trends in pervasive computing and medical informatics are creating the possibility
for large-scale collection, sharing, aggregation and analysis of unprecedented volumes of …

Modelling idiopathic Parkinson disease as a complex illness can inform incidence rate in healthy adults: the PREDIGT score

MG Schlossmacher, JJ Tomlinson… - European Journal of …, 2017 - Wiley Online Library
Fifty‐five years after the concept of dopamine replacement therapy was introduced,
Parkinson disease (PD) remains an incurable neurological disorder. To date, no disease …

Concurrence of high fat diet and APOE gene induces allele specific metabolic and mental stress changes in a mouse model of Alzheimer's disease

Y Segev, A Livne, M Mints… - Frontiers in behavioral …, 2016 - frontiersin.org
Aging is the main risk factor for neurodegenerative diseases, including Alzheimer's disease
(AD). However, evidence indicates that the pathological process begins long before actual …

Development and evaluation of a free e-learning program on dementia risk reduction for the general public: A pre-post study

S Van Asbroeck, SCPM Wimmers… - Journal of …, 2025 - journals.sagepub.com
Background There is consistent evidence for the contribution of modifiable risk factors to
dementia risk, offering opportunities for primary prevention. Yet, most individuals are …

Brain health and dementia prevention: a mixed-method analysis

ZA Marcum, SD Hohl, SL Gray… - American journal of …, 2019 - ingentaconnect.com
Objective: In this study, we assessed patient knowledge, beliefs, and attitudes about brain
health and strategies for Alzheimer's disease and related dementias (ADRD) prevention …