Radical cascade cyclization of 1, n-enynes and diynes for the synthesis of carbocycles and heterocycles

J Xuan, A Studer - Chemical Society Reviews, 2017 - pubs.rsc.org
Carbo-and heterocycles are widely found in natural products, biologically active structures,
medicinally relevant compounds, and in many other fine chemicals. The development of …

Radical Cascade Cyclization of Alkene‐Tethered Compounds: Versatile Approach towards Ring‐Fused Polycyclic Structures

H Liu, L Wang, JT Yu - Asian Journal of Organic Chemistry, 2023 - Wiley Online Library
Ring‐fused polycyclic structures widely exist in a myriad of natural products and
pharmaceutical molecules. Consequently, the construction of such structures from readily …

Divergent gC3N4-catalyzed Reactions of Quinoxalin-2(1H)-ones with N-Aryl Glycines under Visible Light: Solvent-Controlled Hydroaminomethylation and …

YF Si, XL Chen, XY Fu, K Sun, X Song… - ACS Sustainable …, 2020 - ACS Publications
An effective and simple visible light-induced heterogeneous g-C3N4-catalyzed
decarboxylative reaction of quinoxalin-2 (1 H)-ones with N-aryl glycines was developed …

Radical-mediated oxidative annulations of 1, n-enynes involving C–H functionalization

Y Li, GA Pan, MJ Luo, JH Li - Chemical Communications, 2020 - pubs.rsc.org
The 1, n-enyne annulation reaction has emerged as one of the most powerful and
straightforward tools to build carbo-and hetero-cyclic frameworks that are found in numerous …

Synthesis of fused pyran derivatives via visible-light-induced cascade cyclization of 1, 7-enynes with acyl chlorides

CG Li, GQ Xu, PF Xu - Organic letters, 2017 - ACS Publications
A photocatalytic cascade cyclization of 1, 7-enynes with acyl chlorides has been
established. This method offers an operationally simple access to diverse fused pyran …

Aliphatic aldehydes: Novel radical alkylating reagents

WC Yang, JG Feng, L Wu… - Advanced Synthesis & …, 2019 - Wiley Online Library
The emergence of radical chemistry has driven chemists to develop general and efficient
radical reactions as well as to discover safe and cost‐effective radical sources. Among the …

Recent advances in radical-mediated [2+2+m] annulation of 1,n-enynes

CH Xu, Y Li, JH Li, JN Xiang, W Deng - Science China Chemistry, 2019 - Springer
Abstract 1, n-Enynes are a versatile class of unsaturated hydrocarbons that find broad
applications in the synthetic community of natural products, biologically active structures and …

N-Radical enabled cyclization of 1, n-enynes

WT Wei, Q Li, MZ Zhang, WM He - Chinese Journal of Catalysis, 2021 - Elsevier
Compared to the widely used carbon-centered radicals, N-radicals have been relatively
unexplored owing to the lack of practical and convenient production methods. Over the past …

One-Carbon Incorporation Using Cyclobutanone Oxime Ester Enabled [2+ 2+ 1] Carboannulation of 1, 7-Enynes by C–C/N–O Bond Cleavage and C–H …

JX Yu, F Teng, JN Xiang, W Deng, JH Li - Organic letters, 2019 - ACS Publications
A NiCl2-promoted [2+ 2+ 1] carboannulation of 1, 7-enynes with internally oxidative
cyclobutanone oximes to produce canyo-functionalized 4 H-cyclopenta [c] quinolin-4-ones is …

Copper-Catalyzed C–H Oxidative Radical Functionalization and Annulation of Aniline-Linked 1, 7-Enynes: Evidence for a 1, 5-Hydride Shift Mechanism

M Hu, HX Zou, RJ Song, JN Xiang, JH Li - Organic letters, 2016 - ACS Publications
A new copper-catalyzed tandem C–H oxidative radical functionalization and annulation of
aniline-linked 1, 7-enynes with alkyl nitriles or acetone is described. This reaction allows the …