Molecular mechanisms that govern infection and antifungal resistance in Mucorales

C Lax, FE Nicolás, E Navarro… - … and Molecular Biology …, 2024 - Am Soc Microbiol
SUMMARY The World Health Organization has established a fungal priority pathogens list
that includes species critical or highly important to human health. Among them is the order …

Focusing COVID-19-associated mucormycosis: a major threat to immunocompromised COVID-19

N Sharma, SN Wani, T Behl, S Singh, I Zahoor… - … Science and Pollution …, 2023 - Springer
COVID-19 disease has been identified to cause remarkable increase of mucormycosis
infection cases in India, with the majority of cases being observed in individuals recovering …

GRP78 and integrins play different roles in host cell invasion during mucormycosis

A Alqarihi, T Gebremariam, Y Gu, M Swidergall… - MBio, 2020 - Am Soc Microbiol
Mucormycosis, caused by Rhizopus species, is a life-threatening fungal infection that occurs
in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy …

cotH Genes Are Necessary for Normal Spore Formation and Virulence in Mucor lusitanicus

C Szebenyi, Y Gu, T Gebremariam, S Kocsubé… - MBio, 2023 - Am Soc Microbiol
Mucormycosis is an invasive fungal infection caused by certain members of the fungal order
of Mucorales. The species most frequently identified as the etiological agents of …

Novel intravenous immunoglobulin therapy for the prevention and treatment of Candida auris and candida albicans disseminated candidiasis

H Xin, JA Rosario-Colon, K Eberle - MSphere, 2023 - Am Soc Microbiol
Disseminated candidiasis is a life-threatening disease and remains the most common
bloodstream infection in hospitalized patients in the United States. Despite the availability of …

Novel approaches in the management of mucormycosis

F Lamoth - Current Fungal Infection Reports, 2023 - Springer
Abstract Purpose of Review Invasive mucormycosis (IM), caused by fungi of the order
Mucorales, is one of the deadliest fungal infection among hematologic cancer patients. Its …

Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy

E Puumala, S Nabeela, CC Thornburg… - Antimicrobial Agents …, 2024 - journals.asm.org
Fungal disease affects over a billion people worldwide. Naamidine A inhibits the growth of
diverse fungal pathogens through an unknown mechanism. Here, we show that the …

Efficacy of an oral lipid nanocrystal formulation of amphotericin B (MAT2203) in the neutropenic mouse model of pulmonary mucormycosis

Y Gu, T Gebremariam, S Alkhazraji… - Antimicrobial Agents …, 2024 - Am Soc Microbiol
Invasive mucormycosis (IM) is associated with high mortality and morbidity. MAT2203 is an
orally administered lipid nanocrystal formulation of amphotericin B, which has been shown …

H3K4 methylation regulates development, DNA repair, and virulence in Mucorales

M Osorio-Concepción, C Lax, D Lorenzo-Gutiérrez… - IMA fungus, 2024 - Springer
Mucorales are basal fungi that opportunistically cause a potentially fatal infection known as
mucormycosis (black fungus disease), which poses a significant threat to human health due …

[PDF][PDF] GRP78 and integrins play different roles in host cell invasion during mucormycosis. mBio 11: e01087-20

A Alqarihi, T Gebremariam, Y Gu, M Swidergall… - 2020 - researchgate.net
Mucormycosis, caused by Rhizopus species, is a life-threatening fungal infection that occurs
in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy …