[HTML][HTML] How caffeic acid and its derivatives combat diabetes and its complications: A systematic review

I Akhlaghipour, AN Shad, VR Askari, A Maharati… - Journal of Functional …, 2023 - Elsevier
Caffeic acid (CA) and its derivatives, caffeic acid phenyl ethyl amide (CAPA) and caffeic acid
phenyl ester (CAPE), were shown to have anti-oxidant, anti-inflammatory, and anti-diabetic …

[HTML][HTML] Antidiabetic compounds from medicinal plants traditionally used for the treatment of diabetes in Africa: A review update (2015–2020)

A Mohammed, N Tajuddeen - South african journal of botany, 2022 - Elsevier
Africa has a rich biodiversity of plants and an active traditional medicine system that takes
advantage of the rich biodiversity to treat various diseases, including diabetes mellitus (DM) …

Identification of potential human pancreatic α-amylase inhibitors from natural products by molecular docking, MM/GBSA calculations, MD simulations, and ADMET …

S Basnet, MP Ghimire, TR Lamichhane, R Adhikari… - Plos one, 2023 - journals.plos.org
Human pancreatic α-amylase (HPA), which works as a catalyst for carbohydrate hydrolysis,
is one of the viable targets to control type 2 diabetes. The inhibition of α-amylase lowers …

A comprehensive insight into the effects of caffeic acid (CA) on pepsin: Multi-spectroscopy and MD simulations methods

F Hashemi-Shahraki, B Shareghi, S Farhadian… - … Acta Part A: Molecular …, 2023 - Elsevier
The interaction between caffeic acid (CA) and pepsin was investigated using multi-
spectroscopy approaches and molecular dynamic simulations (MDS). The effects of CA on …

[PDF][PDF] Trado-medical uses, chemical constituents and biological activities of Newbouldia laevis (Bignoniaceae): a review

IU Okagu, JC Ndefo, MO Agbo - Pharmaceutical Sciences, 2021 - sid.ir
Abstract Newbouldia laevis (P. Beauv.) Seem.(Family, Bignoniaceae), commonly known as
tree of life, is a purple-flowering plant that is widely distributed in many parts of Africa …

Antioxidant, Alpha‐Amylase Inhibitory and Hypoglycemic Activity of Smallanthus sonchifolius Leaves from Nepal: An Integrated In Vitro, In Vivo, and In Silico …

P Rawal, B Pandey, RK Yadav… - Food Science & …, 2024 - Wiley Online Library
ABSTRACT In 2019, diabetes mellitus affected 9.3% of the global population and accounted
for one in nine adult deaths. Plant‐based antioxidants neutralize harmful free radicals …

Enhanced antibacterial, antioxidant and anticancer activity of caffeic acid by simple acid-base complexation with spermine/spermidine

H Mude, A Balapure, A Thakur, R Ganesan… - Natural Product …, 2022 - Taylor & Francis
Caffeic acid (CA) is a naturally occurring plant-derived polyphenol possessing diverse
biological properties. However, the poor water-solubility of CA restricts its widespread …

Uses of African Plants and Associated Indigenous Knowledge for the Management of Diabetes Mellitus

JA Asong, PT Ndhlovu, A Olatunde, AO Aremu - Diabetology, 2024 - mdpi.com
Diabetes mellitus (DM) is a common non-communicable and chronic metabolic disorder
regarded as a global epidemic with high morbidity and mortality. Although, conventional …

[PDF][PDF] Uses of African Plants and Associated Indigenous Knowledge for the Management of Diabetes Mellitus. Diabetology 2024, 5, 476–490

JA Asong, PT Ndhlovu, A Olatunde, AO Aremu - 2024 - researchgate.net
Diabetes mellitus (DM) is a common non-communicable and chronic metabolic disorder
regarded as a global epidemic with high morbidity and mortality. Although, conventional …

[HTML][HTML] Inhibition of oxidative stress and gastric emptying as additional mechanisms of antidiabetic activity of Newbouldia laevis

IS Mbagwu, PA Akah, AA Ajaghaku, OC Ugwu… - Phytomedicine Plus, 2021 - Elsevier
The quest to fill the gap in knowledge about the antidiabetic activity of the leaf extract of
Newbouldia laevis has inspired further exploration of its possible mechanisms of …