Simple Summary Leukemia, the most common form of childhood cancer, accounts for about
30 percent of all cancers that affect children and young adults. Although pain is a common …

The ongoing opioid epidemic has been a global concern for years, increasingly due to its
heavy toll on young people's lives and prospects. Few studies have investigated trends in …

Background Medicine prescribing for children is impacted by a lack of paediatric‐specific
dosing, efficacy and safety data for many medicines. Objectives To estimate the prevalence …

Despite growing global concern over opioids, little is known about the epidemiology of
opioid use in children and adolescents. This retrospective study investigated opioid use …

Health Canada (HC) has, since 2013, issued safety alerts restricting the use of codeine-
containing drugs among breastfeeding women and children/adolescents under 18 years of …

Background Opioid misuse in the paediatric population is understudied. This study aimed to
develop a machine learning classifier to differentiate between occasional and sustained …

Codeine use was restricted in 2013 and is currently contraindicated for children below the
age of 12 years. We examined how the prescription of opioid analgesics in children in …

Background Prescribing opioids for children and adolescents should be reserved for
advanced life‐limiting diseases and moderate‐to‐severe acute pain. Pediatric codeine use …

Aim To describe time trends in opioid exposures in children under 5 years, and to describe
patient demographics, the medicines involved, the reasons for exposure and disposition …

Australia has reported an increase in opioid overdose deaths, from 2· 2 deaths per 100 000
people in 2006, to 4· 8 deaths per 100 000 people in 2017, many of which were due to …