Management of status epilepticus, refractory status epilepticus, and super-refractory status epilepticus

E Trinka, M Leitinger - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
PURPOSE OF REVIEW Status epilepticus is a serious condition caused by disorders and
diseases that affect the central nervous system. In status epilepticus, hypersynchronous …

Status epilepticus in adults

JP Betjemann, DH Lowenstein - The Lancet Neurology, 2015 - thelancet.com
Status epilepticus is a common neurological emergency with considerable associated
health-care costs, morbidity, and mortality. The definition of status epilepticus as a prolonged …

Epidemiology of status epilepticus in adults: a population‐based study on incidence, causes, and outcomes

M Leitinger, E Trinka, G Giovannini, G Zimmermann… - …, 2019 - Wiley Online Library
Summary Objective In 2015, the International League Against Epilepsy (ILAE) proposed a
new definition of status epilepticus (SE): 5 minutes of ongoing seizure activity to diagnose …

Incidence, cause, and short-term outcome of convulsive status epilepticus in childhood: prospective population-based study

RFM Chin, BGR Neville, C Peckham, H Bedford… - The Lancet, 2006 - thelancet.com
Background Convulsive status epilepticus is the most common childhood medical
neurological emergency, and is associated with significant morbidity and mortality. Most …

EFNS guideline on the management of status epilepticus in adults

H Meierkord, P Boon, B Engelsen… - European journal of …, 2010 - Wiley Online Library
The objective of the current article was to review the literature and discuss the degree of
evidence for various treatment strategies for status epilepticus (SE) in adults. We searched …

Pharmacotherapy for status epilepticus

E Trinka, J Höfler, M Leitinger, F Brigo - Drugs, 2015 - Springer
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …

Management of refractory status epilepticus in adults: still more questions than answers

AO Rossetti, DH Lowenstein - The Lancet Neurology, 2011 - thelancet.com
Refractory status epilepticus (RSE) is defined as status epilepticus that continues despite
treatment with benzodiazepines and one antiepileptic drug. RSE should be treated promptly …

Costs, length of stay, and mortality of super‐refractory status epilepticus: a population‐based study from Germany

A Strzelczyk, S Ansorge, J Hapfelmeier… - …, 2017 - Wiley Online Library
Objective Super‐refractory status epilepticus (SRSE) is a severe condition in which a patient
in status epilepticus (SE) for≥ 24 h does not respond to first‐, second‐, or third‐line therapy …

Status Epilepticus Severity Score (STESS) A tool to orient early treatment strategy

AO Rossetti, G Logroscino, TA Milligan… - Journal of …, 2008 - Springer
Background Status epilepticus (SE) treatment ranges from small benzodiazepine doses to
coma induction. For some SE subgroups, it is unclear how the risk of an aggressive …

Status epilepticus: pathophysiology and management in adults

JWY Chen, CG Wasterlain - The Lancet Neurology, 2006 - thelancet.com
Summary As in Clark and Prout's classic work, we identify three phases of generalised
convulsive status epilepticus, which we call impending, established, and subtle. We review …