Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple
stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover …

Sulforaphane (SFN) is a molecule within the isothiocyanate (ITC) group of organosulfur
compounds. SFN is a phytochemical commonly found in cruciferous vegetables such as …

The c-Met receptor, also known as the HGF receptor, is one of the most studied tyrosine
kinase receptors, yet its biological functions and activation mechanisms are still not fully …

MET receptor has emerged as a druggable target across several human cancers. Agents
targeting MET and its ligand hepatocyte growth factor (HGF) including small molecules such …

Advances in understanding adult stem cell biology have facilitated the development of novel
cell-based therapies for cancer. Recent developments in conventional therapies (eg, tumor …

Gliomas, particularly high-grade gliomas including glioblastoma (GBM), represent the most
common and malignant types of primary brain cancer in adults, and carry a poor prognosis …

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), which is capable of
selectively inducing apoptosis of cancer cells, is a potential targeted drug for cancer therapy …

Glioblastoma (GB) is one of the most malignant types of central nervous system tumours,
classified as grade IV by the World Health Organization. Despite the therapeutic advances …

Metastasis-associated macrophages (MAM) promote persistent growth of breast cancer cells
at the metastatic site and are, thus, an attractive therapeutic target to treat breast cancer …

Background Liposarcoma (LPS) is a tumor derived from adipose tissue, and has the highest
incidence among soft tissue sarcomas. Dedifferentiated liposarcoma (DDLPS) is a …