DNA methylation is an important regulator of gene transcription, and its role in
carcinogenesis has been a topic of considerable interest in the last few years. Alterations in …

Folate being an important vitamin of B Complex group in our diet plays an important role not
only in the synthesis of DNA but also in the maintenance of methylation reactions in the …

Recent decades have seen an alarming increase in the incidence of cardia gastric
adenocarcinoma (CGA) while noncardia gastric adenocarcinoma (NCGA) has decreased. In …

Background & Aims: Increasing evidence suggests that a low folate intake and impaired
folate metabolism may be implicated in the development of gastrointestinal cancers. We …

BACKGROUND & AIMS:: Low folate intake may increase risk for colorectal cancer by
inducing DNA hypomethylation. This study reports the influence of folate status, DNA …

The role of folate metabolism in cancer development is a topic of much current interest, with
maintenance of adequate folate status tending to show a protective effect. Aberrant …

We investigated the risk factors for venous thrombosis in cancer patients with implantable
ports undergoing chemotherapy. One hundred and seventy one ports were placed in a …

Linxian, a rural county in North Central China, has among the highest rates of esophageal
squamous cell carcinoma (ESCC) and gastric cardia adenocarcinoma (GCA) in the world. Its …

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate,
whose role in gastric carcinogenesis is controversial. The authors performed a meta …

The present study aimed at investigating whether the simultaneous evaluation of
pharmacokinetic, pharmacogenetic and demographic factors could improve prediction on …