Advancing the preclinical study of comorbid neuroHIV and substance use disorders: Current perspectives and future directions
Human immunodeficiency virus (HIV) remains a persistent public health concern throughout
the world. Substance use disorders (SUDs) are a common comorbidity that can worsen …
the world. Substance use disorders (SUDs) are a common comorbidity that can worsen …
HIV, Tat and dopamine transmission
Abstract Human Immunodeficiency Virus (HIV) is a progressive infection that targets the
immune system, affecting more than 37 million people around the world. While …
immune system, affecting more than 37 million people around the world. While …
HIV-1 TAT protein enhances sensitization to methamphetamine by affecting dopaminergic function
Methamphetamine abuse is common among humans with immunodeficiency virus (HIV).
The HIV-1 regulatory protein TAT induces dysfunction of mesolimbic dopaminergic systems …
The HIV-1 regulatory protein TAT induces dysfunction of mesolimbic dopaminergic systems …
The effects of HIV-1 regulatory TAT protein expression on brain reward function, response to psychostimulants and delay-dependent memory in mice
JP Kesby, A Markou, S Semenova - Neuropharmacology, 2016 - Elsevier
Depression and psychostimulant abuse are common comorbidities among humans with
immunodeficiency virus (HIV) disease. The HIV regulatory protein TAT is one of multiple HIV …
immunodeficiency virus (HIV) disease. The HIV regulatory protein TAT is one of multiple HIV …
The role of human dopamine transporter in NeuroAIDS
J Zhu, S Ananthan, CG Zhan - Pharmacology & therapeutics, 2018 - Elsevier
HIV-associated neurocognitive disorder (HAND) remains highly prevalent in HIV infected
individuals and represents a special group of neuropathological disorders, which are …
individuals and represents a special group of neuropathological disorders, which are …
HIV-1 Protein Tat1–72 Impairs Neuronal Dendrites via Activation of PP1 and Regulation of the CREB/BDNF Pathway
Y Liu, D Zhou, J Feng, Z Liu, Y Hu, C Liu, X Kong - Virologica Sinica, 2018 - Springer
Despite the success of combined antiretroviral therapy in recent years, the prevalence of
human immunodeficiency virus (HIV)-associated neurocognitive disorders in people living …
human immunodeficiency virus (HIV)-associated neurocognitive disorders in people living …
Intravenous prenatal nicotine exposure alters METH-induced hyperactivity, conditioned hyperactivity, and BDNF in adult rat offspring
In the USA, approximately 15% of women smoke tobacco cigarettes during pregnancy. In
utero tobacco smoke exposure produces somatic growth deficits like intrauterine growth …
utero tobacco smoke exposure produces somatic growth deficits like intrauterine growth …
HIV-1 transgenic rats display an increase in [3H]dopamine uptake in the prefrontal cortex and striatum
HIV viral proteins within the central nervous system are associated with the development of
neurocognitive impairments in HIV-infected individuals. Dopamine transporter (DAT) …
neurocognitive impairments in HIV-infected individuals. Dopamine transporter (DAT) …
Mini review: Promotion of substance abuse in HIV patients: Biological mediation by HIV-1 Tat protein
TJ Cirino, JP McLaughlin - Neuroscience Letters, 2021 - Elsevier
Despite successful viral suppression by combinatorial anti-retroviral therapy, HIV infection
continues to negatively impact the quality of life of patients by promoting neuropathy and HIV …
continues to negatively impact the quality of life of patients by promoting neuropathy and HIV …
Drosophila: An Emergent Model for Delineating Interactions between the Circadian Clock and Drugs of Abuse
AK De Nobrega, LC Lyons - Neural Plasticity, 2017 - Wiley Online Library
Endogenous circadian oscillators orchestrate rhythms at the cellular, physiological, and
behavioral levels across species to coordinate activity, for example, sleep/wake cycles …
behavioral levels across species to coordinate activity, for example, sleep/wake cycles …