Hydrogels for protein delivery

T Vermonden, R Censi, WE Hennink - Chemical reviews, 2012 - ACS Publications
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations
associated with the extraction and purification of pharmaceutical proteins from animal …

Achieving controlled biomolecule–biomaterial conjugation

CD Spicer, ET Pashuck, MM Stevens - Chemical reviews, 2018 - ACS Publications
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

Injectable, biodegradable hydrogels for tissue engineering applications

H Tan, KG Marra - Materials, 2010 - mdpi.com
Hydrogels have many different applications in the field of regenerative medicine.
Biodegradable, injectable hydrogels could be utilized as delivery systems, cell carriers, and …

Michael addition reactions in macromolecular design for emerging technologies

BD Mather, K Viswanathan, KM Miller… - Progress in Polymer …, 2006 - Elsevier
The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …

[HTML][HTML] Conducting polymer-hydrogels for medical electrode applications

RA Green, S Baek, LA Poole-Warren… - … and technology of …, 2010 - Taylor & Francis
Conducting polymers hold significant promise as electrode coatings; however, they are
characterized by inherently poor mechanical properties. Blending or producing layered …

Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine

MK Nguyen, E Alsberg - Progress in polymer science, 2014 - Elsevier
Polymer hydrogels have been widely explored as therapeutic delivery matrices because of
their ability to present sustained, localized and controlled release of bioactive factors …

Poly (vinyl alcohol)-based hydrogels formed by “click chemistry”

DA Ossipov, J Hilborn - Macromolecules, 2006 - ACS Publications
Novel poly (vinyl alcohols)(PVA) functionalized with pendant acetylene and azide groups
were prepared by carbonyldiimidazole (CDI)-mediated couplings of the amines terminated …

Injectable biomaterials for regenerating complex craniofacial tissues

JD Kretlow, S Young, L Klouda, M Wong… - Advanced …, 2009 - Wiley Online Library
Engineering complex tissues requires a precisely formulated combination of cells,
spatiotemporally released bioactive factors, and a specialized scaffold support system …

Degradable thiol-acrylate photopolymers: polymerization and degradation behavior of an in situ forming biomaterial

AE Rydholm, CN Bowman, KS Anseth - Biomaterials, 2005 - Elsevier
Degradable thiol-acrylate photopolymers are a new class of biomaterials capable of rapidly
polymerizing under physiological conditions upon exposure to UV light, with or without …

Injectable scaffolds for tissue regeneration

Q Hou, A Paul, KM Shakesheff - Journal of Materials Chemistry, 2004 - pubs.rsc.org
Tissue engineering aims to develop functional substitutes for damaged or diseased tissues
through complex constructs of living cells, bioactive molecules and three-dimensional …