PLGA nanoparticle preparations by emulsification and nanoprecipitation techniques: Effects of formulation parameters

KY Hernández-Giottonini, RJ Rodríguez-Córdova… - Rsc Advances, 2020 - pubs.rsc.org
This study presents the influence of the primary formulation parameters on the formation of
poly-DL-lactic-co-glycolic nanoparticles by the emulsification-solvent evaporation, and the …

Dendritic cell-targeting polymer nanoparticle-based immunotherapy for cancer: A review

Y Hu, W Zhang, X Chu, A Wang, Z He, CL Si… - International Journal of …, 2023 - Elsevier
Cancer immunity is dependent on dynamic interactions between T cells and dendritic cells
(DCs). Polymer-based nanoparticles target DC receptors to improve anticancer immune …

How subtle differences in polymer molecular weight affect doxorubicin-loaded PLGA nanoparticles degradation and drug release

N Kumskova, Y Ermolenko, N Osipova… - Journal of …, 2020 - Taylor & Francis
Aims: To evaluate the influence of minor differences in molecular weights of commercially
available low molecular weight PLGA grades on the kinetics of doxorubicin release from the …

Design, evaluation and antimicrobial activity of egyptian propolis-loaded nanoparticles: intrinsic role as a novel and naturally based root canal nanosealer

IA Abdel Raheem, A Abdul Razek… - International journal …, 2019 - Taylor & Francis
Background Propolis is a unique natural adhesive product collected by honeybees. It
contains a diversity of bioactive compounds with reported functional properties such as …

Effect of surfactant on the size and stability of PLGA nanoparticles encapsulating a protein kinase C inhibitor

B Shkodra, C Grune, A Traeger, A Vollrath… - International Journal of …, 2019 - Elsevier
Nowadays many drugs with improved therapeutic efficacy are discovered but cannot be
utilized due to their low solubility and insufficient bioavailability. An example of such a drug …

Surface modification of PLGA nanoparticles with chitosan or Eudragit® RS 100: Characterization, prolonged release, cytotoxicity, and enhanced antimicrobial activity

G Yurtdaş-Kırımlıoğlu, Ş Görgülü - Journal of Drug Delivery Science and …, 2021 - Elsevier
Cefpodoxime proxetil (CEF) is a third-generation cephalosporin that is situated in BCS Class
II with poor oral bioavailability. In current work, poly (lactic-co-glycolide)(PLGA) …

Incorporation of nanoparticles into transplantable decellularized matrices: Applications and challenges

TM Saleh, EA Ahmed, L Yu, HH Kwak… - … Journal of Artificial …, 2018 - journals.sagepub.com
Decellularization of tissues can significantly improve regenerative medicine and tissue
engineering by producing natural, less immunogenic, three-dimensional, acellular matrices …

Fab-conjugated PLGA nanoparticles effectively target cancer cells expressing human CD44v6

PJ Kennedy, F Sousa, D Ferreira, C Pereira, M Nestor… - Acta biomaterialia, 2018 - Elsevier
Targeting of CD44 isoforms containing exon v6 (CD44v6) represents a viable strategy for
the therapy and/or early diagnosis of metastatic cancers of the epithelium (eg gastric and …

Ultrastable and biofunctionalizable conjugated polymer nanoparticles with encapsulated iron for ferroptosis assisted chemodynamic therapy

KA Jasim, AJ Gesquiere - Molecular Pharmaceutics, 2019 - ACS Publications
We report the development of novel tumor-targeted conjugated polymer nanoparticles
(CPNPs) carrying iron for chemodynamic therapy (CDT). Tumor cell killing proceeds through …

Comparison between nanoparticle encapsulation and surface loading for lysosomal enzyme replacement therapy

E Muntimadugu, M Silva-Abreu, G Vives… - International journal of …, 2022 - mdpi.com
Poly (lactide-co-glycolide)(PLGA) nanoparticles (NPs) enhance the delivery of therapeutic
enzymes for replacement therapy of lysosomal storage disorders. Previous studies …