Vibrational spectroscopy is an essential tool in chemical analyses, biological assays, and
studies of functional materials. Over the past decade, various coherent nonlinear vibrational …

Proteins are large, complex molecules responsible for various biological processes.
However, protein misfolding may lead to various life-threatening diseases. Therefore, it is …

Infrared difference spectroscopy probes vibrational changes of proteins upon their
perturbation. Compared with other spectroscopic methods, it stands out by its sensitivity to …

Modern vibrational spectroscopy is more than just an analytical tool. Information about the
electronic structure of a molecule, the strength of its bonds, and its conformational flexibility …

The catalytic power of an electric field depends on its magnitude and orientation with respect
to the reactive chemical species. Understanding and designing new catalysts for …

The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

The identification of isotopic labels by conventional macroscopic techniques lacks spatial
resolution and requires relatively large quantities of material for measurements. We …

Triple bonds, such as that formed between two carbon atoms (ie, C≡ C) or that formed
between one carbon atom and one nitrogen atom (ie, C≡ N), afford unique chemical …

Chemical synthesis is a well‐established method for the preparation in the research
laboratory of multiple‐tens‐of‐milligram amounts of correctly folded, high purity protein …

The nitrile containing Ru (II) polypyridyl complex [Ru (phen) 2 (11, 12-dCN-dppz)] 2+(1) is
shown to act as a sensitive infrared probe of G-quadruplex (G4) structures. UV–visible …