Neutrophils in cancer carcinogenesis and metastasis

S Xiong, L Dong, L Cheng - Journal of hematology & oncology, 2021 - Springer
In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

The neutrophil

GL Burn, A Foti, G Marsman, DF Patel, A Zychlinsky - Immunity, 2021 - cell.com
Neutrophils are immune cells with unusual biological features that furnish potent
antimicrobial properties. These cells phagocytose and subsequently kill prokaryotic and …

Neutrophil diversity and plasticity in tumour progression and therapy

S Jaillon, A Ponzetta, D Di Mitri, A Santoni… - Nature Reviews …, 2020 - nature.com
Neutrophils play a key role in defence against infection and in the activation and regulation
of innate and adaptive immunity. In cancer, tumour-associated neutrophils (TANs) have …

[HTML][HTML] Tumor-associated neutrophils and neutrophil-targeted cancer therapies

H Que, Q Fu, T Lan, X Tian, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Neutrophils are the frontline cells in response to microbial infections and are involved in a
range of inflammatory disorders in the body. In recent years, neutrophils have gained …

Tumour-associated neutrophils in patients with cancer

ME Shaul, ZG Fridlender - Nature reviews Clinical oncology, 2019 - nature.com
The role and importance of neutrophils in cancer has become increasingly apparent over
the past decade. Neutrophils accumulate in the peripheral blood of patients with cancer …

Neutrophil diversity in health and disease

C Silvestre-Roig, ZG Fridlender, M Glogauer… - Trends in …, 2019 - cell.com
New evidence has challenged the outdated dogma that neutrophils are a homogeneous
population of short-lived cells. Although neutrophil subpopulations with distinct functions …

Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung

A Tyagi, S Sharma, K Wu, SY Wu, F Xing, Y Liu… - Nature …, 2021 - nature.com
Smoking has a profound impact on tumor immunity, and nicotine, which is the major
addictive component of smoke, is known to promote tumor progression despite being a non …

Tumor-associated myeloid cells: diversity and therapeutic targeting

A Mantovani, F Marchesi, S Jaillon… - Cellular & molecular …, 2021 - nature.com
Myeloid cells in tumor tissues constitute a dynamic immune population characterized by a
non-uniform phenotype and diverse functional activities. Both tumor-associated …

Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment

M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …

Identification of pyroptosis-related subtypes, the development of a prognosis model, and characterization of tumor microenvironment infiltration in colorectal cancer

W Song, J Ren, R Xiang, C Kong, T Fu - Oncoimmunology, 2021 - Taylor & Francis
Pyroptosis is a newly discovered programmed cell death that is associated with tumor
progression, prognosis, and treatment response. However, the potential roles of pyroptosis …