Gut bacteria play a key role in initiating and maintaining the inflammatory process in the gut
tissues of inflammatory bowel disease (IBD) patients, by supplying antigens or other …

Few microorganisms are as versatile as Escherichia coli. An important member of the
normal intestinal microflora of humans and other mammals, E. coli has also been widely …

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …

In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …

Gram-negative bacteria possess an outer membrane layer which constrains uptake and
secretion of solutes and polypeptides. To overcome this barrier, bacteria have developed …

Enteroaggregative Escherichia coli (EAEC) represents a heterogeneous group of E. coli
strains. The pathogenicity and clinical relevance of these bacteria are still controversial. In …

The genome sequences of two Escherichia coli O104: H4 strains derived from two different
patients of the 2011 German E. coli outbreak were determined. The two analyzed strains …

Bacterial pathogens must execute a prodigious array of complex functions in order to
survive, multiply, and disseminate within mammalian hosts. Virulence determinants are …

We have identified and characterized a secreted protein, designated Pic, which is encoded
on the chromosomes of enteroaggregative Escherichia coli (EAEC) 042 and Shigella …

abstract Enteroaggregative Escherichia coli (EAEC) is emerging as a significant diarrheal
pathogen in multiple population groups. Although most commonly associated with pediatric …