Parasitic protozoa comprise diverse aetiological agents responsible for important diseases
in humans and animals including sleeping sickness, Chagas disease, leishmaniasis …

The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …

A series of dihydropyrido [2, 3-d] pyrimidines have been synthesized and screened for its in
vitro antileishmanial activity profile in promastigote and amastigote models. Compounds 2a …

The available therapeutic treatment for leishmaniasis is inadequate and toxic due to side
effects, expensive and emergence of drug resistance. Affordable and safe antileishmanial …

The progresses made in the field of drug design to combat tropical protozoan parasitic
diseases, such as Chagas' disease, leishmaniasis, and sleeping sickness are discussed …

The introduction of amines onto aromatics without metal catalysts and chemical oxidants is
synthetically challenging. Herein, we report the first example of an electrochemical cross …

A series of 75 guanidine and 2-aminoimidazoline analogue molecules were assayed in vitro
against Trypanosoma brucei rhodesiense STIB900 and Plasmodium falciparum K1. The …

Parasitic infections are widespread in developing countries and frequently associated with
immunocompromised patients in developed countries. Consequently, such infections are …

A series of 2, 4, 6 trisubstituted pyrimidines and triazines have been synthesized and
screened for its in vitro antileishmanial activity profile in promastigote model. Nine …

Two sets of benzimidazole derivatives were synthesised and tested in vitro for activity
against promastigotes of Leishmania tropica and L. infantum. Most of the tested compounds …