Chikungunya and arthritis: An overview
Chikungunya is caused by CHIKV (chikungunya virus), an emerging and re-emerging
arthropod-vectored viral infection that causes a febrile disease with primarily long term …
arthropod-vectored viral infection that causes a febrile disease with primarily long term …
Overview on chikungunya virus infection: from epidemiology to state-of-the-art experimental models
LEC Constant, BF Rajsfus, PH Carneiro… - Frontiers in …, 2021 - frontiersin.org
Chikungunya virus (CHIKV) is currently one of the most relevant arboviruses to public
health. It is a member of the Togaviridae family and alphavirus genus and causes an …
health. It is a member of the Togaviridae family and alphavirus genus and causes an …
Nonstructural proteins of alphavirus—potential targets for drug development
F Abu Bakar, LFP Ng - Viruses, 2018 - mdpi.com
Alphaviruses are enveloped, positive single-stranded RNA viruses, typically transmitted by
arthropods. They often cause arthralgia or encephalitic diseases in infected humans and …
arthropods. They often cause arthralgia or encephalitic diseases in infected humans and …
Mechanisms of innate immune evasion in re-emerging RNA viruses
DY Ma, MS Suthar - Current opinion in virology, 2015 - Elsevier
Highlights•RNA viruses passively evade host detection by masking viral PAMPs and
replicating within vesicles.•Many emerging viruses harbor multiple strategies for innate …
replicating within vesicles.•Many emerging viruses harbor multiple strategies for innate …
Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2
Chikungunya virus (CHIKV)(genus Alphavirus) has a positive-sense RNA genome. CHIKV
nonstructural protein 2 (nsP2) proteolytically processes the viral nonstructural polyprotein …
nonstructural protein 2 (nsP2) proteolytically processes the viral nonstructural polyprotein …
The interplay of viral and host factors in chikungunya virus infection: targets for antiviral strategies
KZ Wong, JJH Chu - Viruses, 2018 - mdpi.com
Chikungunya virus (CHIKV) has re-emerged as one of the many medically important
arboviruses that have spread rampantly across the world in the past decade. Infected …
arboviruses that have spread rampantly across the world in the past decade. Infected …
Chikungunya virus overcomes polyamine depletion by mutation of nsP1 and the opal stop codon to confer enhanced replication and fitness
Polyamines, which are small positively charge molecules present in all cells, play important
roles in the replication of DNA and RNA viruses. Chikungunya virus (CHIKV) relies on …
roles in the replication of DNA and RNA viruses. Chikungunya virus (CHIKV) relies on …
[PDF][PDF] Chikungunya vaccines: An update in 2023
P Roongaraya… - Asian Pacific Journal of …, 2023 - apjai-journal.org
A recent chikungunya outbreak affected 1.5 million cases in more than 60 countries. The
virus causes low mortality but moderate to severe morbidities such as high fever, myalgia …
virus causes low mortality but moderate to severe morbidities such as high fever, myalgia …
Selective estrogen receptor modulators limit alphavirus infection by targeting the viral capping enzyme nsP1
Alphaviruses cause animal or human diseases that are characterized by febrile illness,
debilitating arthralgia, or encephalitis. Selective estrogen receptor modulators (SERMs), a …
debilitating arthralgia, or encephalitis. Selective estrogen receptor modulators (SERMs), a …
Palmitoylated cysteines in chikungunya virus nsP1 are critical for targeting to cholesterol-rich plasma membrane microdomains with functional consequences for viral …
In mammalian cells, alphavirus replication complexes are anchored to the plasma
membrane. This interaction with lipid bilayers is mediated through the viral methyl …
membrane. This interaction with lipid bilayers is mediated through the viral methyl …