Reactive oxygen species (ROS) are well known for their role in mediating both physiological
and pathophysiological signal transduction. Enzymes and subcellular compartments that …

Angiogenesis, a new vessel formation from the pre-existing ones, is essential for embryonic
development, wound repair and treatment of ischemic heart and limb diseases. However …

Excessive reactive oxygen species Revised abstract, especially superoxide anion (O2•−),
play important roles in the pathogenesis of many cardiovascular diseases, including …

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by inappropriate
hyperglycemia due to lack of or resistance to insulin. Patients with DM are frequently afflicted …

atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …

Rationale: The function of Nox4, a source of vascular H2O2, is unknown. Other Nox proteins
were identified as mediators of endothelial dysfunction. Objective: We determined the …

After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Reactive oxygen species (ROS) including superoxide (O2.−) and hydrogen peroxide (H2O2)
are produced endogenously in response to cytokines, growth factors; G-protein coupled …

A new microparticle-based delivery system was synthesized from reactive oxygen species
(ROS)-responsive poly (propylene sulfide)(PPS) and tested for “on demand” antioxidant …

Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and
obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro-and …