Vitiligo: a focus on pathogenesis and its therapeutic implications

C Bergqvist, K Ezzedine - The Journal of dermatology, 2021 - Wiley Online Library
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …

Vitiligo, from pathogenesis to therapeutic advances: state of the art

F Diotallevi, H Gioacchini, E De Simoni… - International Journal of …, 2023 - mdpi.com
Vitiligo is an acquired hypopigmentation of the skin due to a progressive selective loss of
melanocytes; it has a prevalence of 1–2% and appears as rounded, well-demarcated white …

[HTML][HTML] Vitiligo skin is imprinted with resident memory CD8 T cells expressing CXCR3

K Boniface, C Jacquemin, AS Darrigade… - Journal of Investigative …, 2018 - Elsevier
Vitiligo is a chronic autoimmune depigmenting skin disorder that results from a loss of
melanocytes. Multiple combinatorial factors have been involved in disease development …

Phototherapy for vitiligo: a systematic review and meta-analysis

JM Bae, HM Jung, BY Hong, JH Lee, WJ Choi… - JAMA …, 2017 - jamanetwork.com
Importance References to the expected treatment response to phototherapy would be
helpful in the management of vitiligo because phototherapy requires long treatment …

Vitiligo: an update on pathophysiology and treatment options

R Speeckaert, N van Geel - American journal of clinical dermatology, 2017 - Springer
The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo,
early factors include activation of innate immunity, inflammasome activation, oxidative stress …

Current and emerging treatments for vitiligo

M Rodrigues, K Ezzedine, I Hamzavi… - Journal of the American …, 2017 - Elsevier
Clinicians should be aware that vitiligo is not merely a cosmetic disease and that there are
safe and effective treatments available for vitiligo. It is important to recognize common and …

An update on Vitiligo pathogenesis

J Seneschal, K Boniface, A D'Arino… - Pigment cell & …, 2021 - Wiley Online Library
Vitiligo, the most common depigmenting disorder of the skin, is undergoing a period of
intense advances in both disease understanding and therapeutic possibilities leading the …

Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the International Vitiligo Task Force Part 1: towards a new …

N van Geel, R Speeckaert, A Taïeb… - Journal of the …, 2023 - Wiley Online Library
Background The treatment of vitiligo can be challenging and depends on several factors
such as the subtype, disease activity, vitiligo extent, and treatment goals. Vitiligo usually …

The role of memory CD8+ T cells in vitiligo

RL Riding, JE Harris - The Journal of Immunology, 2019 - journals.aai.org
Vitiligo is an autoimmune skin disease mediated by autoreactive CD8+ T cells that destroy
the pigment-producing cells of the epidermis, melanocytes, leading to areas of …

S1 Guideline: Diagnosis and therapy of vitiligo

M Böhm, JA Schunter, K Fritz… - JDDG: Journal der …, 2022 - Wiley Online Library
Vitiligo is a common skin disorder characterized by immune‐mediated destruction of
melanocytes. Non‐segmental vitiligo, the most common clinical subtype, has usually a …