Cytoskeletal disruption after electroporation and its significance to pulsed electric field therapies

PM Graybill, RV Davalos - Cancers, 2020 - mdpi.com
Pulsed electric fields (PEFs) have become clinically important through the success of
Irreversible Electroporation (IRE), Electrochemotherapy (ECT), and nanosecond PEFs …

All wired up: an exploration of the electrical properties of microtubules and tubulin

AP Kalra, BB Eakins, SD Patel, G Ciniero, V Rezania… - ACS …, 2020 - ACS Publications
Microtubules are hollow, cylindrical polymers of the protein α, β tubulin, that interact
mechanochemically with a variety of macromolecules. Due to their mechanically robust …

Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells

L Carr, SM Bardet, RC Burke, D Arnaud-Cormos… - Scientific reports, 2017 - nature.com
High powered, nanosecond duration, pulsed electric fields (nsPEF) cause cell death by a
mechanism that is not fully understood and have been proposed as a targeted cancer …

No observable non-thermal effect of microwave radiation on the growth of microtubules

G Hammarin, P Norder, R Harimoorthy, G Chen… - Scientific reports, 2024 - nature.com
Despite widespread public interest in the health impact of exposure to microwave radiation,
studies of the influence of microwave radiation on biological samples are often inconclusive …

Assessment of molecular modulation by multifrequency electromagnetic pulses to preferably eradicate tumorigenic cells

R Piredda, LGR Martínez, K Stamatakis… - Scientific Reports, 2024 - nature.com
Physics methods of cancer therapy are extensively used in clinical practice, but they are
invasive and often confront undesired side effects. A fully new equipment that allows …

Electro-acoustic behavior of the mitotic spindle: a semi-classical coarse-grained model

D Havelka, O Kučera, MA Deriu, M Cifra - PLoS One, 2014 - journals.plos.org
The regulation of chromosome separation during mitosis is not fully understood yet.
Microtubules forming mitotic spindles are targets of treatment strategies which are aimed at …

Tubulin assembly is disordered in a hypogeomagnetic field

DL Wang, XS Wang, R Xiao, Y Liu, RQ He - Biochemical and Biophysical …, 2008 - Elsevier
Although the effect of a magnetic field on functions of many proteins has been reported,
tubulin assembly in a hypogeomagnetic field (HGMF) has not yet been characterized. Here …

Flow patterns and defect dynamics of active nematic liquid crystals under an electric field

Y Kinoshita, N Uchida - Physical Review E, 2023 - APS
The effects of an electric field on the flow patterns and defect dynamics of two-dimensional
active nematic liquid crystals are numerically investigated. We found that field-induced …

Ion permeability of a microtubule in neuron environment

C Shen, W Guo - The journal of physical chemistry letters, 2018 - ACS Publications
Microtubules, constituted by end-to-end negatively charged α-and β-tubulin dimers, are
long, hollow, pseudohelical cylinders with internal and external diameters of about 16 and …

Electromagnetic fields and stem cell fate: when physics meets biology

SH Tamrin, FS Majedi, M Tondar… - Reviews of Physiology …, 2016 - Springer
Controlling stem cell (SC) fate is an extremely important topic in the realm of SC research. A
variety of different external cues mainly mechanical, chemical, or electrical stimulations …