Germ cell formation and embryonic development require ATP synthesized by mitochondria.
The dynamic system of the mitochondria, and in particular, the fusion of mitochondria, are …

Mitochondria are organelles that serve numerous critical cellular functions, including energy
production, Ca2+ homeostasis, redox signaling, and metabolism. These functions are …

The large cytosolic GTPase, dynamin-related protein 1 (Drp1), mediates both physiological
and pathological mitochondrial fission. Cell stress triggers Drp1 binding to mitochondrial …

Breast cancer, due to resistance to standard therapies such as endocrine therapy, anti-
HER2 therapy and chemotherapy, continues to pose a major health challenge. A growing …

A dispersed cytoplasmic distribution of mitochondria is a hallmark of normal cellular
organization. Here, we have utilized the expression of exogenous Trak2 in mouse oocytes …

As the cell's energy factory and metabolic hub, mitochondria are critical for ATP synthesis to
maintain cellular function. Mitochondria are highly dynamic organelles that continuously …

Wound healing is vital for human health, yet the details of cellular dynamics and
coordination in human wound repair remain largely unexplored. To address this, we …

Kearns-Sayre syndrome (KSS) is a rare multisystem mitochondrial disorder. It is caused by
mitochondrial DNA (mtDNA) rearrangements, mostly large-scale deletions of 1.1–10 kb …

Deregulation of mitochondria activity is one of the hallmarks of cancerogenesis and an
important target for cancer therapy. Therefore, we compared the impact of an active form of …

Human multipotent mesenchymal stromal/stem cells (MSCs) have been utilized in cell
therapy for various diseases and their clinical applications are expected to increase in the …