Biological processes (like microbial growth & physiological response) are usually dynamic
and require the monitoring of metabolic variation at different time-points. Moreover, there is …

Owing to drug synergy effects, drug combinations have become a new trend in combating
complex diseases like cancer, HIV and cardiovascular diseases. However, conventional …

Vaccination has been tremendously successful saving lives and preventing infections.
However, the development of vaccines against global pandemics such as HIV, malaria and …

Chronic malaria is a major public health problem and significant challenge for disease
eradication efforts. Despite its importance, the biological factors underpinning chronic …

Highlights•Progress towards a P. falciparum malaria vaccine continues with the completion
of several clinical trials.•Plasmodium vivax vaccine development needs to be prioritized and …

Plasmodium cynomolgi causes zoonotic malarial infections in Southeast Asia and this
parasite species is important as a model for Plasmodium vivax and Plasmodium ovale. Each …

Abstract Background Non-human primates (NHPs), particularly macaques, serve as critical
and highly relevant pre-clinical models of human disease. The similarity in human and …

Background Malaria is a major mosquito transmitted, blood-borne parasitic disease that
afflicts humans. The disease causes anaemia and other clinical complications, which can …

Systemic metabolic reprogramming induced by infection exerts profound, pathogen-specific
effects on infection outcome. Here, we detail the host immune and metabolic response …

Abstract Rhesus macaques (Macaca mulatta, RMs) are widely used in sexual maturation
studies due to their high genetic and physiological similarity to humans. However, judging …