Disentangling in-vivo microstructural changes of white and gray matter in mild cognitive impairment and Alzheimer's disease: A systematic review and meta-analysis
S Zhong, J Lou, K Ma, Z Shu, L Chen, C Li, Q Ye… - Brain Imaging and …, 2023 - Springer
The microstructural characteristics of white and gray matter in mild cognitive impairment
(MCI) and the early-stage of Alzheimer's disease (AD) remain unclear. This study aimed to …
(MCI) and the early-stage of Alzheimer's disease (AD) remain unclear. This study aimed to …
[HTML][HTML] Maintaining brain health across the lifespan
I Garcia-Garcia, O Donica, AA Cohen… - Neuroscience & …, 2023 - Elsevier
Across the lifespan, the human body and brain endure the impact of a plethora of
exogenous and endogenous factors that determine the health outcome in old age. The …
exogenous and endogenous factors that determine the health outcome in old age. The …
MRI and fluid biomarkers reveal determinants of myelin and axonal loss with aging
KA Walker, MR Duggan, Z Gong… - Annals of Clinical …, 2023 - Wiley Online Library
Objective White matter damage is a feature of Alzheimer's disease, yet little is known about
how facets of the Alzheimer's disease process relate to key features of white matter structure …
how facets of the Alzheimer's disease process relate to key features of white matter structure …
[HTML][HTML] Identification of clinically relevant brain endothelial cell biomarkers in plasma
J Cordon, MR Duggan, GT Gomez, KA Pucha, Z Peng… - Stroke, 2023 - journals.lww.com
BACKGROUND: Proteins expressed by brain endothelial cells (BECs), the primary cell type
of the blood-brain barrier, may serve as sensitive plasma biomarkers for neurological and …
of the blood-brain barrier, may serve as sensitive plasma biomarkers for neurological and …
Superficial white matter across development, young adulthood, and aging: volume, thickness, and relationship with cortical features
Superficial white matter (SWM) represents a significantly understudied part of the human
brain, despite comprising a large portion of brain volume and making up a majority of cortico …
brain, despite comprising a large portion of brain volume and making up a majority of cortico …
Lower myelin content is associated with more rapid cognitive decline among cognitively unimpaired individuals
Introduction The influence of myelination on longitudinal changes in cognitive performance
remains unclear. Methods For each participant (N= 123), longitudinal cognitive scores were …
remains unclear. Methods For each participant (N= 123), longitudinal cognitive scores were …
Association of poor oral health with neuroimaging markers of white matter injury in middle-aged participants in the UK Biobank
Background and Objectives Poor oral health is a modifiable risk factor that is associated with
clinically observed cardiovascular disease. However, the relationship between oral and …
clinically observed cardiovascular disease. However, the relationship between oral and …
Neurocognitive Aging
SR Cox - Annual Review of Developmental Psychology, 2024 - annualreviews.org
On average, most aspects of adult human brains and cognitive functions experience decline
with age, yet individuals also differ greatly in how much decline they experience. This review …
with age, yet individuals also differ greatly in how much decline they experience. This review …
Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age
INTRODUCTION We investigated the associations of leptin markers with cognitive function
and magnetic resonance imaging (MRI) measures of brain atrophy and vascular injury in …
and magnetic resonance imaging (MRI) measures of brain atrophy and vascular injury in …
[HTML][HTML] Distinct longitudinal brain white matter microstructure changes and associated polygenic risk of common psychiatric disorders and Alzheimer's disease in the …
Background During the course of adulthood and aging, white matter (WM) structure and
organization are characterized by slow degradation processes such as demyelination and …
organization are characterized by slow degradation processes such as demyelination and …