Current methods for skeletal muscle tissue repair and regeneration

J Liu, D Saul, KO Böker, J Ernst… - BioMed research …, 2018 - Wiley Online Library
Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of
muscle loss, this regeneration needs interventional support. Consequently, muscle injury …

Neurotrophic and neuroregenerative effects of GH/IGF1

VE Bianchi, V Locatelli, L Rizzi - International journal of molecular …, 2017 - mdpi.com
Introduction. Human neurodegenerative diseases increase progressively with age and
present a high social and economic burden. Growth hormone (GH) and insulin-like growth …

Multiple effects of growth hormone in the body: is it really the hormone for growth?

J Devesa, C Almengló… - Clinical Medicine Insights …, 2016 - journals.sagepub.com
In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

Peripheral nerve injury: current challenges, conventional treatment approaches, and new trends in biomaterials-based regenerative strategies

R López-Cebral, J Silva-Correia, RL Reis… - ACS Biomaterials …, 2017 - ACS Publications
Damage to peripheral nerves is a widely extended health problem, causing important
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …

Sustained IGF-1 delivery ameliorates effects of chronic denervation and improves functional recovery after peripheral nerve injury and repair

PJ Hanwright, C Qiu, J Rath, Y Zhou, N von Guionneau… - Biomaterials, 2022 - Elsevier
Functional recovery following peripheral nerve injury is limited by progressive atrophy of
denervated muscle and Schwann cells (SCs) that occurs during the long regenerative …

Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine

X Wang, N Rivera‐Bolanos, B Jiang… - Advanced Functional …, 2019 - Wiley Online Library
Stem cell–based therapies can potentially regenerate many types of tissues and organs,
thereby providing solutions to a variety of diseases and injuries. However, acute cell death …

Use of the CatWalk gait analysis system to assess functional recovery in rodent models of peripheral nerve injury–a systematic review

J Heinzel, G Längle, V Oberhauser, T Hausner… - Journal of Neuroscience …, 2020 - Elsevier
Injuries of the peripheral nervous system are common among the population affecting
around 3% of all trauma patients. This high clinical need in the field of peripheral nerve …

Insulin-like growth factor-1: a promising therapeutic target for peripheral nerve injury

BR Slavin, KA Sarhane, N von Guionneau… - … in bioengineering and …, 2021 - frontiersin.org
Patients who sustain peripheral nerve injuries (PNIs) are often left with debilitating sensory
and motor loss. Presently, there is a lack of clinically available therapeutics that can be given …

Translational bioengineering strategies for peripheral nerve regeneration: opportunities, challenges, and novel concepts

KA Sarhane, C Qiu, TGW Harris… - Neural Regeneration …, 2023 - journals.lww.com
Peripheral nerve injuries remain a challenging problem in need of better treatment
strategies. Despite best efforts at surgical reconstruction and postoperative rehabilitation …

Exercise and muscle atrophy

N He, H Ye - Physical exercise for human health, 2020 - Springer
The incidence of muscle atrophy is increasing with each passing year, which imposes a
huge burden on the quality of life of patients. It is a public health issue that causes a growing …