Acute hypoxic–ischemic encephalopathy around the time of birth remains a major cause of
death and life-long disability. The key insight that led to the modern revival of studies of …

The possibility that hypothermia during or after resuscitation from asphyxia at birth, or
cardiac arrest in adults, might reduce evolving damage has tantalized clinicians for a very …

This executive summary provides the essential treatment algorithms for the resuscitation of
children and adults and highlights the main guideline changes since 2010. Detailed …

JP Nolan et al./Resuscitation 95 (2015) 202–222 203 from 39 countries reviewed thousands
of relevant, peer-reviewed publications to address 169 specific resuscitation questions, each …

Background: Therapeutic hypothermia (TH) after cardiac arrest protects from neurological
sequels and death and is recommended in guidelines. The Hypothermia Registry was …

Background and Purpose—Induced hypothermia is a promising neuroprotective therapy.
We studied the feasibility and safety of hypothermia and thrombolysis after acute ischemic …

Background A hypoxic-ischaemic insult occurring around the time of birth may result in an
encephalopathic state characterised by the need for resuscitation at birth, neurological …

Objective. Cerebral hypothermia has been shown to reduce damage from experimental hy-
poxia-ischemia if started shortly after reperfusion. However, in the newborn infant it may not …

Intracerebral hemorrhage (ICH) is characterized by parenchymal hematoma formation with
surrounding inflammation. Matrix metalloproteinases (MMPs) have been implicated in the …

Study objective: To examine the effects of moderate hypothermia (33° C), induced by
surface cooling in the ED and maintained for 12 hours in the ICU, on patients with anoxic …