Recent advances in development of dendritic polymer‐based nanomedicines for cancer diagnosis

H Li, J Sun, H Zhu, H Wu, H Zhang… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Dendritic polymers have highly branched three‐dimensional architectures, the fourth type
apart from linear, cross‐linked, and branched one. They possess not only a large number of …

Detection and clinical significance of circulating tumor cells in colorectal cancer

M Jiang, S Jin, J Han, T Li, J Shi, Q Zhong, W Li… - Biomarker …, 2021 - Springer
Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …

An avidity-based PD-L1 antagonist using nanoparticle-antibody conjugates for enhanced immunotherapy

J Bu, A Nair, M Iida, W Jeong, MJ Poellmann… - Nano …, 2020 - ACS Publications
Upregulation of programmed death ligand 1 (PD-L1) allows cancer cells to evade antitumor
immunity. Despite tremendous efforts in developing PD-1/PD-L1 immune checkpoint …

Bimodal liquid biopsy for cancer immunotherapy based on peptide engineering and nanoscale analysis

J Bu, W Jeong, R Jafari, LJ Kubiatowicz, A Nair… - Biosensors and …, 2022 - Elsevier
Despite its high potential, PD-L1 expressed by tumors has not been successfully utilized as
a biomarker for estimating treatment responses to immunotherapy. Circulating tumor cells …

Circulating tumor cell abundance in head and neck squamous cell carcinoma decreases with successful chemoradiation and cetuximab treatment

MJ Poellmann, J Bu, DW Kim, M Iida, H Hong… - Cancer letters, 2023 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is a common and deadly cancer.
Circulating tumor cell (CTC) abundance may a valuable, prognostic biomarker in low-and …

Nanomedicine for renal cell carcinoma: imaging, treatment and beyond

R Wu, K Wang, Y Gai, M Li, J Wang, C Wang… - Journal of …, 2023 - Springer
The kidney is a vital organ responsible for maintaining homeostasis in the human body.
However, renal cell carcinoma (RCC) is a common malignancy of the urinary system and …

Nanotechnology and machine learning enable circulating tumor cells as a reliable biomarker for radiotherapy responses of gastrointestinal cancer patients

MJ Poellmann, J Bu, S Liu, AZ Wang… - Biosensors and …, 2023 - Elsevier
A highly sensitive, circulating tumor cell (CTC)-based liquid biopsy was used to monitor
gastrointestinal cancer patients during treatment to determine if CTC abundance was …

Dendrimers for cancer immunotherapy: Avidity‐based drug delivery vehicles for effective anti‐tumor immune response

PA Rawding, J Bu, J Wang, DW Kim… - Wiley …, 2022 - Wiley Online Library
Cancer immunotherapy, or the utilization of a patient's own immune system to treat cancer,
has shifted the paradigm of cancer treatment. Despite meaningful responses being …

Magnetically-activated, nanostructured cellulose for efficient capture of circulating tumor cells from the blood sample of head and neck cancer patients

RS Hazra, N Kale, C Boyle, KB Molina, A D'Souza… - Carbohydrate …, 2024 - Elsevier
In this report, the relative efficiency of cellulose nanocrystals (CNCs) and nanofibers (CNFs)
to capture circulating tumor cells (CTCs) from the blood sample of head and neck cancer …

A review of recent progress toward the efficient separation of circulating tumor cells via micro‐/nanostructured microfluidic chips

X Liu, L Ma, W Yan, A Aazmi, M Fang, X Xu, H Kang… - View, 2022 - Wiley Online Library
Circulating tumor cells (CTCs) are closely correlated with cancer diagnoses, and their early
detection can help patients receive accurate prognoses in a noninvasive manner. However …