This review provides information on the biological activities of chalcones (whether natural or
synthetic derivatives) on different organisms, as well as an overview of the functions and …

Leishmaniases are endemic diseases in tropical and sub-tropical regions of the world and
are considered by the World Health Organization (WHO) to be among the six most important …

Leishmania parasites infect macrophages causing a wide spectrum of human diseases
encompassing from cutaneous to visceral forms. The drugs currently used in leishmaniasis …

Two types of regioisomeric chromene‐based chalcones namely, 1‐(6‐methoxy‐2H‐
chromen‐3‐yl)‐3‐phenylpropen‐1‐ones and 3‐(6‐methoxy‐2H‐chromen‐3‐yl)‐1 …

The treatment of American cutaneous leishmaniasis (ACL) is based on a small group of
compounds that were developed decades ago, all of which are highly toxic and have a high …

Improved therapies for inflammatory bowel diseases are sorely needed. Novel therapeutic
agents and the development of controlled release systems for targeted tissue delivery are …

Cutaneous leishmaniasis is a worldwide public health problem. Conventional therapies, in
addition to the high cost, have many adverse effects and cases of parasite's resistance …

Background Chemotherapy is a principle tool for the control and prevention of
piroplasmosis. The search for a new chemotherapy against Babesia and Theileria parasites …

Despite clinical importance of leishmaniasis, an infectious disease that affects 12 thousand
million people in 88 countries, the treatment is still unsatisfactory due to its limited efficacy …

The Leishmaniasis treatment currently available involves some difficulties, such as high
toxicity, variable efficacy, high cost, therefore, it is crucial to search for new therapeutic …