Physiological and behavioral mechanisms of thermoregulation in mammals

D Mota-Rojas, CG Titto, A Orihuela, J Martínez-Burnes… - Animals, 2021 - mdpi.com
Simple Summary The study of the hypothalamic neuromodulation of thermoregulation offers
broad areas of opportunity with practical applications that are currently being strengthened …

Patch-seq: Past, present, and future

M Lipovsek, C Bardy, CR Cadwell… - Journal of …, 2021 - Soc Neuroscience
Single-cell transcriptomic approaches are revolutionizing neuroscience. Integrating this
wealth of data with morphology and physiology, for the comprehensive study of neuronal …

A discrete neuronal circuit induces a hibernation-like state in rodents

TM Takahashi, GA Sunagawa, S Soya, M Abe… - Nature, 2020 - nature.com
Hibernating mammals actively lower their body temperature to reduce energy expenditure
when facing food scarcity. This ability to induce a hypometabolic state has evoked great …

An airway-to-brain sensory pathway mediates influenza-induced sickness

NR Bin, SL Prescott, N Horio, Y Wang, IM Chiu… - Nature, 2023 - nature.com
Pathogen infection causes a stereotyped state of sickness that involves neuronally
orchestrated behavioural and physiological changes,. On infection, immune cells release a …

Neurons that regulate mouse torpor

S Hrvatin, S Sun, OF Wilcox, H Yao, AJ Lavin-Peter… - Nature, 2020 - nature.com
The advent of endothermy, which is achieved through the continuous homeostatic regulation
of body temperature and metabolism,, is a defining feature of mammalian and avian …

[HTML][HTML] Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals

D Sang, K Lin, Y Yang, G Ran, B Li, C Chen, Q Li, Y Ma… - Cell, 2023 - cell.com
Most animals require sleep, and sleep loss induces serious pathophysiological
consequences, including death. Previous experimental approaches for investigating sleep …

Temperature sensation: from molecular thermosensors to neural circuits and coding principles

R Xiao, XZS Xu - Annual review of physiology, 2021 - annualreviews.org
Temperature is a universal cue and regulates many essential processes ranging from
enzymatic reactions to species migration. Due to the profound impact of temperature on …

Interactions between central nervous system and peripheral metabolic organs

W Zeng, F Yang, WL Shen, C Zhan, P Zheng… - Science China Life …, 2022 - Springer
According to Descartes, minds and bodies are distinct kinds of “substance”, and they cannot
have causal interactions. However, in neuroscience, the two-way interaction between the …

Estrogen-sensitive medial preoptic area neurons coordinate torpor in mice

Z Zhang, FMCV Reis, Y He, JW Park… - Nature …, 2020 - nature.com
Homeotherms maintain a stable internal body temperature despite changing environments.
During energy deficiency, some species can cease to defend their body temperature and …

[HTML][HTML] Linking transcriptomes with morphological and functional phenotypes in mammalian retinal ganglion cells

W Huang, Q Xu, J Su, L Tang, ZZ Hao, C Xu, R Liu… - Cell Reports, 2022 - cell.com
Retinal ganglion cells (RGCs) are the brain's gateway to the visual world. They can be
classified into different types on the basis of their electrophysiological, transcriptomic, or …