Evolutionary constraint and innovation across hundreds of placental mammals
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …
Priority effects transcend scales and disciplines in biology
Although primarily studied through the lens of community ecology, phenomena consistent
with priority effects appear to be widespread across many different scenarios spanning a …
with priority effects appear to be widespread across many different scenarios spanning a …
Comparative transcriptomics reveals human-specific cortical features
The cognitive abilities of humans are distinctive among primates, but their molecular and
cellular substrates are poorly understood. We used comparative single-nucleus …
cellular substrates are poorly understood. We used comparative single-nucleus …
The contribution of historical processes to contemporary extinction risk in placental mammals
Species persistence can be influenced by the amount, type, and distribution of diversity
across the genome, suggesting a potential relationship between historical demography and …
across the genome, suggesting a potential relationship between historical demography and …
Insights into mammalian TE diversity through the curation of 248 genome assemblies
We examined transposable element (TE) content of 248 placental mammal genome
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …
assemblies, the largest de novo TE curation effort in eukaryotes to date. We found that …
Genomes, fossils, and the concurrent rise of modern birds and flowering plants in the Late Cretaceous
S Wu, FE Rheindt, J Zhang, J Wang… - Proceedings of the …, 2024 - National Acad Sciences
The phylogeny and divergence timing of the Neoavian radiation remain controversial
despite recent progress. We analyzed the genomes of 124 species across all Neoavian …
despite recent progress. We analyzed the genomes of 124 species across all Neoavian …
A timescale for placental mammal diversification based on Bayesian modeling of the fossil record
The timing of the placental mammal radiation has been the focus of debate over the efficacy
of competing methods for establishing evolutionary timescales. Molecular clock analyses …
of competing methods for establishing evolutionary timescales. Molecular clock analyses …
Imbalanced speciation pulses sustain the radiation of mammals
The evolutionary histories of major clades, including mammals, often comprise changes in
their diversification dynamics, but how these changes occur remains debated. We combined …
their diversification dynamics, but how these changes occur remains debated. We combined …
Murine trophoblast organoids as a model for trophoblast development and CRISPR-Cas9 screening
Q Mao, Q Ye, Y Xu, J Jiang, Y Fan, L Zhuang, G Liu… - Developmental Cell, 2023 - cell.com
The placenta becomes one of the most diversified organs during placental mammal
radiation. The main in vitro model for studying mouse trophoblast development is the 2D …
radiation. The main in vitro model for studying mouse trophoblast development is the 2D …
Chiropterans are a hotspot for horizontal transfer of DNA transposons in Mammalia
Horizontal transfer of transposable elements (TEs) is an important mechanism contributing
to genetic diversity and innovation. Bats (order Chiroptera) have repeatedly been shown to …
to genetic diversity and innovation. Bats (order Chiroptera) have repeatedly been shown to …