The Haematopoietically expressed homeobox transcription factor (Hhex) is a transcriptional
repressor that is of fundamental importance across species, as evident by its evolutionary …

Human embryonic stem cells (hESCs) are derived from the inner cell mass (ICM) of the pre-
implantation blastocyst. Prior to embryo implantation, the ICM cells are surrounded by …

With the discovery and development of somatic cell nuclear transfer, cell fusion, and induced
pluripotent stem cells, cell transdifferentiation research has presented unique advantages …

Retinoic acid (RA) is essential for gut endoderm development and has been extensively
used for in vitro pancreatic differentiation from human pluripotent stem cells. However, the …

Pluripotent stem cells (PSCs) hold enormous potential for treating multiple diseases owing
to their ability to self‐renew and differentiate into any cell type. Albeit possessing such …

Polycomb group proteins (PcGs) add repressive post translational histone modifications
such as H2AK119ub1, and histone H2A deubiquitinases remove it. Mice lacking histone …

During embryogenesis, the first pancreatic cells arise from a region located in the posterior
foregut. Different signals are important to induce the formation of both the ventral and dorsal …

Embryonic stem cells (ESCs) have been shown to have an ability to form a large number of
functional endothelial cells in vitro, but generating organ-specific endothelial cells remains a …

Linoleic acid (LA) has been shown to cause inflammation and promote development of
colorectal cancer (CRC). Moreover, many literatures show that LA is associated with cancer …

There are two entities of ectopic spleen: Accessory spleen (AS), which is a congenital
condition and originates in a fusion failure of splenic buds of the dorsal mesogastrium in the …