Structural plasticity and reorganisation in chronic pain
Chronic pain is not simply a temporal continuum of acute pain. Studies on functional
plasticity in neural circuits of pain have provided mechanistic insights and linked various …
plasticity in neural circuits of pain have provided mechanistic insights and linked various …
Clinical updates on phantom limb pain
Methods: This review aims to provide an interdisciplinary overview of recent evidence-based
and clinical knowledge. Results: The scientific evidence for best practice is weak and …
and clinical knowledge. Results: The scientific evidence for best practice is weak and …
Primary motor cortex changes after amputation correlate with phantom limb pain and the ability to move the phantom limb
A substantial body of evidence documents massive reorganization of primary sensory and
motor cortices following hand amputation, the extent of which is correlated with phantom …
motor cortices following hand amputation, the extent of which is correlated with phantom …
Leg prosthesis with somatosensory feedback reduces phantom limb pain and increases functionality
C Dietrich, S Nehrdich, S Seifert, KR Blume… - Frontiers in …, 2018 - frontiersin.org
Phantom limb pain (PLP) develops in most patients with lower limb amputation. Changes in
the peripheral and central nervous system (CNS) are hypothesized to contribute to PLP …
the peripheral and central nervous system (CNS) are hypothesized to contribute to PLP …
[HTML][HTML] Reaffirming the link between chronic phantom limb pain and maintained missing hand representation
Phantom limb pain (PLP) is commonly considered to be a result of maladaptive brain
plasticity. This model proposes that PLP is mainly caused by reorganisation in the primary …
plasticity. This model proposes that PLP is mainly caused by reorganisation in the primary …
Pain, from perception to action: a computational perspective
ZS Chen, J Wang - Iscience, 2023 - cell.com
Pain is driven by sensation and emotion, and in turn, it motivates decisions and actions. To
fully appreciate the multidimensional nature of pain, we formulate the study of pain within a …
fully appreciate the multidimensional nature of pain, we formulate the study of pain within a …
Cortical plasticity as a basis of phantom limb pain: Fact or fiction?
Cortical reorganization has been proposed as a major factor involved in phantom pain with
prior nociceptive input to the deafferented region and input from the non-deafferented cortex …
prior nociceptive input to the deafferented region and input from the non-deafferented cortex …
Mathematical and computational models for pain: a systematic review
Objective There is no single prevailing theory of pain that explains its origin, qualities, and
alleviation. Although many studies have investigated various molecular targets for pain …
alleviation. Although many studies have investigated various molecular targets for pain …
Capsaicin 8% patch treatment for amputation stump and phantom limb pain: a clinical and functional MRI study
R Privitera, R Birch, M Sinisi, IR Mihaylov… - Journal of pain …, 2017 - Taylor & Francis
Purpose The aim of this study was to measure the efficacy of a single 60 min application of
capsaicin 8% patch in reducing chronic amputation stump and phantom limb pain …
capsaicin 8% patch in reducing chronic amputation stump and phantom limb pain …
Disentangling the effects of spinal cord injury and related neuropathic pain on supraspinal neuroplasticity: a systematic review on neuroimaging
Background: Spinal cord injury (SCI) and its accompanying changes of brain structure and
function have been widely studied and reviewed. Debilitating chronic neuropathic pain (NP) …
function have been widely studied and reviewed. Debilitating chronic neuropathic pain (NP) …