The wall gives a Saccharomyces cerevisiae cell its osmotic integrity; defines cell shape
during budding growth, mating, sporulation, and pseudohypha formation; and presents …

The cell wall of Saccharomyces cerevisiae is an elastic structure that provides osmotic and
physical protection and determines the shape of the cell. The inner layer of the wall is largely …

Prions are proteins that convert between structurally and functionally distinct states, one or
more of which is transmissible. In yeast, this ability allows them to act as non-Mendelian …

The biological sciences are undergoing an explosion in the amount of available data. New
data analysis methods are needed to deal with the data. We present work using KDD to …

Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental
problem in biology. Here, we describe how a single assay can be used to monitor hundreds …

The chemical composition of many fungal cell walls is known, but we have not understood
the interactions of the various macromolecules nor the assembly processes. The …

An extracellular matrix composed of a layered meshwork of β-glucans, chitin, and
mannoproteins encapsulates cells of the yeast Saccharomyces cerevisiae. This organelle …

SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

The fungal cell wall is an essential organelle and represents a considerable metabolic
investment. Its macromolecular composition, molecular organization and thickness can vary …

Our knowledge of the yeast cell wall has increased rapidly in the past few years, allowing for
the first time a description of its structure in molecular terms. Two types of cell wall proteins …