MicroRNAs as potential biomarkers in cancer: opportunities and challenges

H Lan, H Lu, X Wang, H Jin - BioMed research international, 2015 - Wiley Online Library
MicroRNAs (miRNAs) are a group of small noncoding RNAs (ncRNAs) that
posttranscriptionally regulate gene expression by targeting their corresponding messenger …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

A microfluidics-based in vitro model of the gastrointestinal human–microbe interface

P Shah, JV Fritz, E Glaab, MS Desai… - Nature …, 2016 - nature.com
Abstract Changes in the human gastrointestinal microbiome are associated with several
diseases. To infer causality, experiments in representative models are essential, but widely …

MicroRNAs as peripheral biomarkers in aging and age-related diseases

S Kumar, M Vijayan, JS Bhatti, PH Reddy - Progress in molecular biology …, 2017 - Elsevier
MicroRNAs (miRNAs) are found in the circulatory biofluids considering the important
molecules for biomarker study in aging and age-related diseases. Blood or blood …

Phosphatidylserine: A cancer cell targeting biomarker

B Sharma, SS Kanwar - Seminars in cancer biology, 2018 - Elsevier
Cancer is a leading cause of mortality and morbidity globally. Many prominent cancer-
associated molecules have been identified over the recent years which include EGFR …

Hypoxia induces drug resistance in colorectal cancer through the HIF-1α/miR-338-5p/IL-6 feedback loop

K Xu, Y Zhan, Z Yuan, Y Qiu, H Wang, G Fan, J Wang… - Molecular Therapy, 2019 - cell.com
Hypoxia is associated with poor prognosis and therapeutic resistance in cancer patients.
Accumulating evidence has shown that microRNA (miRNA) plays an important role in the …

IL (Interleukin)-6 contributes to deep vein thrombosis and is negatively regulated by miR-338-5p

Y Zhang, Z Zhang, R Wei, X Miao, S Sun… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Deep venous thrombosis (DVT), one of the most common venous
thromboembolic disorders, is closely linked with pulmonary embolism and post-thrombotic …

Colorectal cancer biomarkers: where are we now?

M Gonzalez-Pons… - BioMed research …, 2015 - Wiley Online Library
Colorectal cancer is one of the major causes of cancer‐related death in the Western world.
Patient survival is highly dependent on the tumor stage at the time of diagnosis. Reduced …

Dissecting miRNA signature in colorectal cancer progression and metastasis

X Huang, X Zhu, Y Yu, W Zhu, L Jin, X Zhang, S Li… - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

Serum-based microRNA signatures in early diagnosis and prognosis prediction of colon cancer

P Vychytilova-Faltejskova, L Radova… - …, 2016 - academic.oup.com
Early detection of colorectal cancer is the main prerequisite for successful treatment and
reduction of mortality. Circulating microRNAs were previously identified as promising …