The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

Smokeless tobacco consumption, which is widespread throughout the world, leads to oral
submucous fibrosis (OSMF), which is a long-lasting and devastating condition of the oral …

This report reviews the literature on the genotoxicity of mainstream tobacco smoke and
cigarette smoke condensate (CSC) published since 1985. CSC is genotoxic in nearly all …

The single cell gel electrophoresis or Comet assay is a sensitive, reliable, and rapid method
for DNA double-and single-strand breaks, alkali-labile sites and delayed repair site …

The comet assay is widely used in human biomonitoring to measure DNA damage as a
marker of exposure to genotoxic agents or to investigate genoprotective effects. Studies …

The comet assay is the method of choice for measuring DNA damage, of various sorts, in
human cells such as lymphocytes obtained in the course of population-based studies of …

Within the last decade, the comet assay has been used with increasing popularity to
investigate the level of DNA damage in terms of strand breaks and alkaline labile sites in …

Human biomonitoring using the single cell gel electrophoresis (SCGE) or comet assay is a
novel approach for the assessment of genetic damage in exposed populations. This assay …

Hazardous chemicals in the environment and diet or their electrophilic metabolites can form
adducts with genomic DNA, which can lead to mutations and the initiation of cancer. In …

Tobacco smoking causes not only lung cancer but also cancer of the oral and nasal cavities,
oesophagus, larynx, pharynx, pancreas, liver, kidney, stomach, urinary tract and cervix …