Exciting advances in fluorescence in situ hybridization and array-based techniques are
changing the nature of cytogenetics, in both basic research and molecular diagnostics …

Fluorescence in situ hybridization (FISH) is an effective and accurate cytogenetic tool for
mapping single copy and repetitive DNA sequences on chromosomes. Attempts to increase …

A novel secreted glycoprotein that regulates bone resorption has been identified. The
protein, termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily …

We report the cloning of a gene, intronless in its coding region, which we have named APJ.
This gene was cloned using the polymerase chain reaction (PCR), with a set of primers …

The G protein-coupled receptor (GPCR) family share a structural motif of seven
transmembrane segments with large numbers of conserved residues in those regions. Here …

A light microscope-based technique for rapidly constructing ordered physical maps of
chromosomes has been developed. Restriction enzyme digestion of elongated individual …

The cytosolic protein APAF1, human homolog of C. elegans CED-4, participates in the
CASPASE 9 (CASP9)-dependent activation of CASP3 in the general apoptotic pathway. We …

We have identified a novel transformation-sensitive mRNA, which is present in cultured
fibroblasts but is lacking in SV40 transformed cells as well as in many mesenchymal tumor …

We have investigated the possible implication of the cell cycle‐regulated K+ channel ether à
go‐go (EAG) in cell proliferation and transformation. We show that transfection of EAG into …

Methionine synthase catalyzes the remethylation of homocysteine to methionine via a
reaction in which methylcobalamin serves as an intermediate methyl carrier. Over time, the …