Metabolomics for investigating physiological and pathophysiological processes

DS Wishart - Physiological reviews, 2019 - journals.physiology.org
Metabolomics uses advanced analytical chemistry techniques to enable the high-throughput
characterization of metabolites from cells, organs, tissues, or biofluids. The rapid growth in …

Fluorescent probes with multiple binding sites for the discrimination of Cys, Hcy, and GSH

CX Yin, KM Xiong, FJ Huo… - Angewandte Chemie …, 2017 - Wiley Online Library
Biothiols such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) play crucial
roles in maintaining redox homeostasis in biological systems. This Minireview summarizes …

Homocysteine modification in protein structure/function and human disease

H Jakubowski - Physiological reviews, 2019 - journals.physiology.org
Epidemiological studies established that elevated homocysteine, an important intermediate
in folate, vitamin B12, and one carbon metabolism, is associated with poor health, including …

Homocysteine-induced endothelial dysfunction

WKC Lai, MY Kan - Annals of Nutrition and Metabolism, 2015 - karger.com
This review discussed and in particular emphasis the potential cellular pathways and the
biological processes involved that lead to homocysteine-induced endothelial dysfunction, in …

Homocysteine: its possible emerging role in at-risk population groups

E Azzini, S Ruggeri, A Polito - International journal of molecular sciences, 2020 - mdpi.com
Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

[HTML][HTML] Predictors for imaging progression on chest CT from coronavirus disease 2019 (COVID-19) patients

Z Yang, J Shi, Z He, Y Lü, Q Xu, C Ye, S Chen… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Objective: This study aimed to investigate the potential parameters associated with imaging
progression on chest CT from coronavirus disease 19 (COVID-19) patients. Results: The …

DNA methylation as a biomarker for cardiovascular disease risk

M Kim, TI Long, K Arakawa, R Wang, MC Yu, PW Laird - PloS one, 2010 - journals.plos.org
Background Elevated serum homocysteine is associated with an increased risk of
cardiovascular disease (CVD). This may reflect a reduced systemic remethylation capacity …

The effects of vitamin B in depression

K Mikkelsen, L Stojanovska… - Current medicinal …, 2016 - ingentaconnect.com
Vitamins are dietary components which are necessary for life. They play a major role in
health and their deficiency may be linked to symptoms of psychiatric disorders. B vitamins …

Mechanisms of homocysteine toxicity in humans

J Perła-Kaján, T Twardowski, H Jakubowski - Amino acids, 2007 - Springer
Homocysteine, a non-protein amino acid, is an important risk factor for ischemic heart
disease and stroke in humans. This review provides an overview of homocysteine influence …

[图书][B] Folate in health and disease

LB Bailey - 2009 - taylorfrancis.com
During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …