Acute-on-chronic liver failure in cirrhosis

V Arroyo, R Moreau, PS Kamath, R Jalan… - Nature reviews Disease …, 2016 - nature.com
The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and
North America, the term is generally applied according to the European Association for the …

Model for end-stage liver disease

AK Singal, PS Kamath - Journal of clinical and experimental hepatology, 2013 - Elsevier
Model for end-stage liver disease (MELD) score, initially developed to predict survival
following transjugular intrahepatic portosystemic shunt was subsequently found to be …

Management of patients with liver diseases on the waiting list for transplantation: a major impact to the success of liver transplantation

D Samuel, A Coilly - BMC medicine, 2018 - Springer
Background The results of liver transplantation are excellent, with survival rates of over 90
and 80% at 1 and 5 years, respectively. The success of liver transplantation has led to an …

[PDF][PDF] Patients with acute on chronic liver failure grade 3 have greater 14‐day waitlist mortality than status‐1a patients

V Sundaram, P Shah, RJ Wong, CJ Karvellas… - …, 2019 - Wiley Online Library
Patients listed for liver transplantation (LT) as status 1a currently receive the highest priority
on the waiting list. The presence of acute on chronic liver failure (ACLF) with three or more …

AASLD Practice guidance on Acute-on-chronic liver failure and the management of critically Ill patients with cirrhosis

CJ Karvellas, JS Bajaj, PS Kamath, L Napolitano… - Hepatology, 2024 - journals.lww.com
The clinical stages of cirrhosis have traditionally been divided into a compensated phase
with no complications and a decompensated phase that manifests with complications of …

Extracorporeal liver support in patients with liver failure: a systematic review and meta-analysis of randomized trials

F Alshamsi, K Alshammari, E Belley-Cote… - Intensive care …, 2020 - Springer
Purpose Acute liver failure (ALF) and acute on chronic liver failure (ACLF) are associated
with significant mortality and morbidity. Extracorporeal liver support (ECLS) devices have …

Acute-on-chronic liver failure

SK Asrani, DA Simonetto, PS Kamath - Clinical gastroenterology and …, 2015 - Elsevier
Over the past 2 decades, the concept of acute-on-chronic liver failure (ACLF) has been
proposed as an alternate path in the natural history of decompensated cirrhosis. ACLF thus …

[HTML][HTML] Current status of liver allocation in the United States

S Elwir, J Lake - Gastroenterology & hepatology, 2016 - ncbi.nlm.nih.gov
The liver transplant allocation system is currently based upon the Model for End-Stage Liver
Disease (MELD) score and allocates organs preferentially to patients with the highest scores …

A critical review of MELD as a reliable tool for transplant prioritization

SC Sacleux, D Samuel - Seminars in liver disease, 2019 - thieme-connect.com
In a context of global organ shortage, the Model for End-Stage Liver Disease (MELD) score
seems to be a fair prioritization tool, with a paradigm:“sickest first.” Since its introduction in …

[HTML][HTML] Evolution of liver transplant organ allocation policy: current limitations and future directions

A Polyak, A Kuo, V Sundaram - World Journal of Hepatology, 2021 - ncbi.nlm.nih.gov
Since the adoption of the model for end-stage liver disease (MELD) score for organ
allocation in 2002, numerous changes to the system of liver allocation and distribution have …