American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an
estimated 1.5 million new cases per year. In Brazil, ACL represents a significant public …

The aim of the study was to investigate whether polymorphisms in genes encoding Toll-like
receptors (TLR2 and TLR4) may modify relative risk for development of asthma or allergic …

Upon the invasion of the host by microorganisms, innate immunity is triggered through
pathogen recognition by pattern recognition receptors (PRRs). Toll-like receptors (TLRs) are …

Leishmaniases are neglected tropical diseases with a broad clinical spectrum. Tegumentary
leishmaniasis (TL) is a disease caused by different Leishmania species, transmitted by …

Visceral leishmaniasis (VL) is endemic in the Mediterranean basin and leads to the most
severe form of Leishmania infection, lethal if left untreated. However, most infections are sub …

Macrophages are the primary host cell for Leishmania parasites, by Toll like receptors (TLR-
MyD88) that are central components of the innate and adaptive immunity against leishmania …

Objectives The outcomes of tegumentary leishmaniasis (TL) rely on a complex interaction
between the host immune system and the parasite. This study assessed the influence of …

Recurrence of hydatid cysts in cystectomy patients has dramatically remained a serious
concern within the surgical community. Predisposing factors for recurrence of hydatid cysts …

Os receptores do tipo toll (toll-like receptors ou TLRs) são uma família de receptores na
primeira linha de defesa do sistema imune inato que são capazes de reconhecer padrões …