Structure of the bacterial ribosome at 2 Å resolution

ZL Watson, FR Ward, R Méheust, O Ad, A Schepartz… - elife, 2020 - elifesciences.org
Using cryo-electron microscopy (cryo-EM), we determined the structure of the Escherichia
coli 70S ribosome with a global resolution of 2.0 Å. The maps reveal unambiguous …

Receptor-based screening assays for the detection of antibiotics residues–a review

S Ahmed, J Ning, G Cheng, I Ahmad, J Li, L Mingyue… - Talanta, 2017 - Elsevier
Consumer and regulatory agencies have a high concern to antibiotic residues in food
producing animals, so appropriate screening assays of fast, sensitive, low cost, and easy …

Visualization of chemical modifications in the human 80S ribosome structure

SK Natchiar, AG Myasnikov, H Kratzat, I Hazemann… - Nature, 2017 - nature.com
Chemical modifications of human ribosomal RNA (rRNA) are introduced during biogenesis
and have been implicated in the dysregulation of protein synthesis, as is found in cancer …

Visualizing the role of 2'-OH rRNA methylations in the human ribosome structure

SK Natchiar, AG Myasnikov, I Hazemann, BP Klaholz - Biomolecules, 2018 - mdpi.com
Chemical modifications of RNA have recently gained new attention in biological sciences.
They occur notably on messenger RNA (mRNA) and ribosomal RNA (rRNA) and are …

Impact of homologous recombination on the evolution of prokaryotic core genomes

P González-Torres, F Rodríguez-Mateos, J Antón… - MBio, 2019 - Am Soc Microbiol
Homologous recombination (HR) enables the exchange of genetic material between and
within species. Recent studies suggest that this process plays a major role in the …

Evolution of Antibiotic Resistance in Surrogates of Francisella tularensis (LVS and Francisella novicida): Effects on Biofilm Formation and Fitness

FV Biot, BA Bachert, KD Mlynek, RG Toothman… - Frontiers in …, 2020 - frontiersin.org
Francisella tularensis, the causative agent of tularemia, is capable of causing disease in a
multitude of mammals and remains a formidable human pathogen due to a high morbidity …

Genome-Wide Association Analyses in the Model Rhizobium Ensifer meliloti

B Epstein, RAI Abou-Shanab, A Shamseldin… - MSphere, 2018 - Am Soc Microbiol
Genome-wide association studies (GWAS) can identify genetic variants responsible for
naturally occurring and quantitative phenotypic variation. Association studies therefore …

Population Genetics and Antimicrobial Susceptibility of Canine Campylobacter Isolates Collected before and after a Raw Feeding Experiment

S Olkkola, S Kovanen, J Roine, ML Hänninen… - PloS one, 2015 - journals.plos.org
In recent years, increasing numbers of consumers have become interested in feeding raw
food for their pet dogs as opposed to commercial dry food, in the belief of health advantages …

[HTML][HTML] Genetic variations underlying aminoglycoside resistance in antibiotic-induced Mycobacterium intracellulare mutants

HE Park, JI Shin, KM Kim, JG Choi, WJ Anh… - Infection, Genetics and …, 2025 - Elsevier
Mycobacterium avium complex (MAC) is an emerging pathogen leading to public health
concerns in developing and developed countries, particularly among immunocompromised …

RNA modification enzymes encoded by the gid operon: Implications in biology and virulence of bacteria

DC Shippy, AA Fadl - Microbial pathogenesis, 2015 - Elsevier
Ribonucleic acid (RNA) molecules consist of numerous chemically modified nucleosides
that are highly conserved in eukarya, archeae, and bacteria, while others are unique to each …