With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers …

Background: Nowadays, ionizing radiations are used for various medical and terroristic
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …

Aging involves a decline in neural function that contributes to cognitive impairment and
disease. However, the mechanisms underlying the transition from a young-and-healthy to …

Radiation‐induced myocardial fibrosis (RIMF) is a potentially lethal clinical complication of
chest radiotherapy (RT) and a final stage of radiation‐induced heart disease (RIHD). RIMF is …

Normal tissue injury from irradiation is an unfortunate consequence of radiotherapy.
Technologic improvements have reduced the risk of normal tissue injury; however, toxicity …

Cancer management has undergone significant improvements, which led to increased long-
term survival rates among cancer patients. Radiotherapy (RT) has an important role in the …

Protection of normal tissues against toxic effects of ionizing radiation is a critical issue in
clinical and environmental radiobiology. Investigations in recent decades have suggested …

Background and purpose The effects of radiation on the heart are dependent on dose,
fractionation, overall treatment time, and pre-existing cardiovascular pathology. Murine …

Acute exposure to high dose radiation can cause acute radiation syndrome (ARS), a
potentially life-threatening illness. Individuals that survive ARS are at risk of developing the …

The transcription factor Nrf2 is an important modulator of antioxidant and drug metabolism,
carbohydrate and lipid metabolism, as well as heme and iron metabolism. Regulation of …