Histotripsy: a method for mechanical tissue ablation with ultrasound

Z Xu, TD Khokhlova, CS Cho… - Annual Review of …, 2024 - annualreviews.org
Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …

[HTML][HTML] From concept to early clinical trials: 30 years of microbubble-based ultrasound-mediated drug delivery research

A Bouakaz, JM Escoffre - Advanced Drug Delivery Reviews, 2024 - Elsevier
Ultrasound mediated drug delivery, a promising therapeutic modality, has evolved
remarkably over the past three decades. Initially designed to enhance contrast in ultrasound …

First-in-human prospective trial of sonobiopsy in high-grade glioma patients using neuronavigation-guided focused ultrasound

J Yuan, L Xu, CY Chien, Y Yang, Y Yue… - NPJ Precision …, 2023 - nature.com
Sonobiopsy is an emerging technology that combines focused ultrasound (FUS) with
microbubbles to enrich circulating brain disease-specific biomarkers for noninvasive …

[HTML][HTML] Barrier-breaking effects of ultrasonic cavitation for drug delivery and biomarker release

Y Hu, J Wei, Y Shen, S Chen, X Chen - Ultrasonics Sonochemistry, 2023 - Elsevier
Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …

Surface behaviors of droplet manipulation in microfluidics devices

L Wu, Z Guo, W Liu - Advances in Colloid and Interface Science, 2022 - Elsevier
In recent years, the rapid development of microfluidic technology has caused a revolutionary
impact in the fields of chemistry, medicine, and life sciences. Also, droplet control is one of …

Focused ultrasound–mediated liquid biopsy in a tauopathy mouse model

CP Pacia, J Yuan, Y Yue, EC Leuthardt, TLS Benzinger… - Radiology, 2023 - pubs.rsna.org
Background Neurodegenerative disorders (such as Alzheimer disease) characterized by the
deposition of various pathogenic forms of tau protein in the brain are collectively referred to …

Binary acoustic metasurfaces for dynamic focusing of transcranial ultrasound

Z Hu, Y Yang, L Xu, Y Hao, H Chen - Frontiers in Neuroscience, 2022 - frontiersin.org
Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive and
spatially targeted neuromodulation and treatment of brain diseases. Acoustic lenses were …

Adding value to liquid biopsy for brain tumors: The role of imaging

N Khalili, H Shooli, N Hosseini, A Fathi Kazerooni… - Cancers, 2023 - mdpi.com
Simple Summary Clinical management in neuro-oncology has shifted to an integrated
method that combines molecular profiles with histopathological and imaging data. Liquid …

Strategies, considerations, and recent advancements in the development of liquid biopsy for glioblastoma: a step towards individualized medicine in glioblastoma

MMJ Bauman, SM Bouchal, DD Monie, A Aibaidula… - Neurosurgical …, 2022 - thejns.org
OBJECTIVE Glioblastoma (GBM) is a devasting primary brain tumor with less than a 5% 5-
year survival. Treatment response assessment can be challenging because of inflammatory …

Airy-beam-enabled binary acoustic metasurfaces for underwater ultrasound-beam manipulation

Z Hu, Y Yang, L Xu, Y Jing, H Chen - Physical review applied, 2022 - APS
Airy beams are peculiar beams that are nondiffracting, self-accelerating, and self-healing,
and they have offered great opportunities for ultrasound-beam manipulation. However, one …