Sequence database search engines are bioinformatics algorithms that identify peptides from
tandem mass spectra using a reference protein sequence database. Two decades of …

PatternLab for proteomics is an integrated computational environment that unifies several
previously published modules for the analysis of shotgun proteomic data. The contained …

The recent improvements in mass spectrometry instruments and new analytical methods are
increasing the intersection between proteomics and big data science. In addition …

Chemical cross-linking has emerged as a powerful approach for the structural
characterization of proteins and protein complexes. However, the correct identification of …

Cross-linking coupled with mass spectrometry (XL-MS) has emerged as a powerful strategy
for the identification of protein–protein interactions, characterization of interaction regions …

Background: Bothrops atrox is known to be the pit viper responsible for most snakebites and
human fatalities in the Amazon region. It can be found in a wide geographical area including …

The study of snake venom proteomes (venomics) has been experiencing a burst of reports,
however the comprehensive knowledge of the dynamic range of proteins present within a …

Peptide spectrum matching is the current gold standard for protein identification via mass-
spectrometry-based proteomics. Peptide spectrum matching compares experimental mass …

The complete sequence characterization of snake venom proteins by mass spectrometry is
rather challenging due to the presence of multiple isoforms from different protein families. In …

Simple Summary We developed a clinical proteomics methodology, known as Wise MS
Transfer (WiMT), for deep identification of blood proteins in undepleted plasma samples. We …